Formulation of Ibuprofen Beads by Ionotropic Gelation
| Author | Payam Khazaeli | en |
| Author | Abbas Pardakhty | en |
| Author | Fereshteh Hassanzadeh | en |
| Issued Date | 2008-07-31 | en |
| Abstract | Microencapsulation has become a common technique in the production of controlled release dosage forms. Many results have been reported, concerning the use of alginate beads as controlled release drug formulations. Alginate has a unique gel-forming property in the presence of multivalent cations, in an aqueous medium. Ibuprofen is an excellent analgesic and antipyretic, non-steroidal anti-inflammatory agent with a high therapeutic index. Formulation of ibuprofen in beads could reduce its gastric ulcerogenicity. Hence, in this study the formation of Ca-alginate ibuprofen beads, through ionotropic gelation has been investigated. | en |
| DOI | https://doi.org/10.22037/ijpr.2010.761 | en |
| Keyword | Na-alginate | en |
| Keyword | Drug release | en |
| Keyword | Bead formulatin | en |
| Keyword | Ionotropic gelation | en |
| Keyword | Microencapsulation | en |
| Keyword | Ibuprofen | en |
| Publisher | Brieflands | en |
| Title | Formulation of Ibuprofen Beads by Ionotropic Gelation | en |
| Type | Research Article | en |