Prevalence of Chronic Hepatitis B and Hepatitis C among First Time Blood Donors in Northeast Bosnia and Herzegovina: An Estimate of Prevalence in General Population
| Author | Jasminka Petrovic | en |
| Author | Nermin N. Salkic | en |
| Author | Sead Ahmetagic | en |
| Author | Vildana Stojic | en |
| Author | Slavica Mott-Divkovic | en |
| Issued Date | 2011-08-31 | en |
| Abstract | Background: Data on the epidemiology of hepatitis B and C in Bosnia and Herzegovina (B&H) are lacking.Objectives: To assess the prevalence of hepatitis B surface antigen (HBsAg) and anti-hepatitis C virus (anti-HCV) in blood samples of first time blood donors in a well-defined region of B&H. Our secondary goal was to estimate the prevalence of HBsAg and anti-HCV in the general population of the same region.Patients and Methods: We evaluated 8196 blood samples for the presence of HBsAg and/or anti-HCV, adjusted for differences in gender, and used the ratio estimation method to determine the prevalence in the general population.Results: We analyzed 1263 (15.4%) female and 6933 (84.6%) male blood donors (male-to-female ratio: 5.49 to 1). The adjusted prevalence of HBsAg among blood donors was 0.787% (95% CI = 0.535-1.038), while the prevalence of anti-HCV was 0.267% (95% CI = 0.016-0.519). There was no difference in the prevalence of HBsAg or anti-HCV between men and women. We estimate that the prevalence of HBsAg and anti-HCV in the general population is 1.057% to 1.535% and 0.29% to 0.89%, respectively.Conclusions: The prevalence of HBsAg and anti-HCV among blood donors suggests that our region has low endemicity for both hepatitis B and hepatitis C.Keywords: Hepatitis B; Hepatitis C virus; Epidemiology; Blood donors; Population; Bosnia and Herzegovina Implication for health policy/practice/research/medical education: Up to date there is no accurate data on prevalence of chronic hepatitis B and C among blood donors in Bosnia and Herzegovina. Additionally, estimates of prevalence of general population suggest that prior assessments were inaccurate. Please cite this paper as: Petrovic J, Salkic NN, Ahmetagic S, Stojic V, Mott-Divkovic S. Prevalence of Chronic Hepatitis B and Hepatitis C among First Time Blood Donors in Northeast Bosnia and Herzegovina: An Estimate of Prevalence in General Population. Hepat Mon. 2011;11(8):629-33. [DOI: 10.5812/kowsar.1735143X.716] Copyright © 2011 Kowsar M.P.Co. All rights reserved. | en |
| DOI | https://doi.org/10.5812/kowsar.1735143X.716 | en |
| Keyword | Hepatitis B | en |
| Keyword | Hepatitis C virus | en |
| Keyword | Epidemiology | en |
| Keyword | Blood donors | en |
| Keyword | Population | en |
| Keyword | Bosnia and Herzegovina | en |
| Publisher | Brieflands | en |
| Title | Prevalence of Chronic Hepatitis B and Hepatitis C among First Time Blood Donors in Northeast Bosnia and Herzegovina: An Estimate of Prevalence in General Population | en |
| Type | Research Article | en |
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