<i>In-vitro</i> Bioactivity and Phytochemical Screening of Extracts from Rhizomes of <i>Eremostachys azerbaijanica</i> rech. f. Growing in Iran

AuthorSolmaz Asnaasharien
AuthorAbbas Delazaren
AuthorParina Asgharianen
AuthorFarzaneh Lotfipouren
AuthorSedigeh Bamdad Moghaddamen
AuthorFariba Heshmati Afsharen
Issued Date2017-01-31en
AbstractThe current study evaluated the general toxicity, antioxidant, antimicrobial, and cytotoxic activity of extracts obtained from the rhizomes of Eremostachys azerbaijanica (Labiatae) as well as analyzed the potent extracts using GC-MS. Extracts of E. azerbaijanica in n-hexane, dichloromethane (DCM) and methanol (MeOH) were prepared using a Soxhlet apparatus. The antioxidant activity of the extracts was evaluated for free radical scavenging activity by DPPH assay. The antimicrobial activity of samples was determined by disc diffusion and brine shrimp lethality assay (BSLA) was used to assess general toxicity. The cytotoxicity of each extract was determined by MTT assay against human colorectal adenocarcinoma (HT29), human lung carcinoma (A549) and a normal cell line (human umbilical vein endothelial cells, HUVEC).en
DOIhttps://doi.org/10.22037/ijpr.2017.1960en
Keyword<i>Eremostachys azerbaijanica</i>en
Keywordgeneral toxicityen
Keywordcytotoxicityen
Keywordantimicrobialen
Keywordantioxidanten
PublisherBrieflandsen
Title<i>In-vitro</i> Bioactivity and Phytochemical Screening of Extracts from Rhizomes of <i>Eremostachys azerbaijanica</i> rech. f. Growing in Iranen
TypeOriginal Articleen

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