Evaluation of marriage and childbirth in patients with non-transfusion-dependent beta thalassemia major at Thalassemia Research Center of Sari, Iran

AuthorMandana Zafarien
AuthorMehnoush Kowsarianen
Issued Date2015-06-30en
AbstractBackground and Purpose: Patients with non-transfusion-dependent beta thalassemia major (NTDTM) could reach old age, marry andhave children with appropriate care. This study aimed to review the marital status and maternal-fetal outcomes of NTDTM patients atThalassemia Research Center (TRC) of Sari, Iran.Methods: In this study, medical records of patients with β-thalassemia major were reviewed from July 2014 to December 2014. Allthe patients were interviewed, and a questionnaire was designated by research methodology experts. Reliability of the questionnaireswas measured through a pilot study on 12 patients using the test-retest method (r=0.9). In addition, epidemiological characteristics andpregnancy outcomes of the patients were recorded. Data analysis was performed using descriptive statistics in SPSS.Results: In total, 419 records were reviewed, and 74 cases (17.6%) had NTDTM. During a 25-year marriage period, 23 pregnancieswere reported with 18 childbirths. Low birth weight was observed in three neonates (23.1%), and there was one assisted pregnancy.In addition, one female NTDTM patient was married to a β-thalassemia carrier and had two abortions (one after prenatal diagnosis).In this study, 24 (32.4%) and 14 (58.3%) male NTDTM patients were married, and only one case had a child. Mean age of marriagein male NTDTM patients was 25.3±4.2 years.Conclusion: According to the results of this study, proper management of NTDTM patients will help them reach the reproductive age.It also seems that fertility is higher among female NTDTM patients.en
DOIhttps://doi.org/10.7508/jnms.2015.02.005en
KeywordChildbirthen
KeywordFertilityen
KeywordInfertilityen
KeywordIntermedia ?-thalassemiaen
KeywordMarriageen
KeywordNon-transfusion-dependent thalassemia majoren
KeywordPregnancyen
PublisherBrieflandsen
TitleEvaluation of marriage and childbirth in patients with non-transfusion-dependent beta thalassemia major at Thalassemia Research Center of Sari, Iranen
TypeResearch Articleen

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