Protective Effects of Vitamin C and NAC on the Toxicity of Rifampin on Hepg₂ Cells

Abstract

Rifampin, an antibiotic widely used for the treatment of mycobacterial infections, produces hepatic, renal and bone marrow toxicity in human and animals. In this study, the protective effects of vitamin C and n-acetylcysteine (NAC) on the toxicity of rifampin on HepG2 cells were investigated.