Docking, Synthesis and Evaluation of the Antifungal Activity of Pyrimido [4,5-b]quinolins
| Author | Reza Araghi | en |
| Author | Bi Bi Fatemeh Mirjalili | en |
| Author | Leila Zamani | en |
| Author | Soghra Khabnadideh | en |
| Author | Kamiar Zomoridian | en |
| Author | Zeinab Faghih | en |
| Author | Hamidreza Arabi | en |
| Issued Date | 2020-01-31 | en |
| Abstract | In order to expand the application of Fe3O4@SiO2-SnCl4 in the synthesis of heterocyclic compounds, in this study, we wish to report the use of one-pot three component synthesis of pyrimido [4,5-b]quinolone derivatives (D1-D16) through reaction of 6-amino-2-(methylthio)pyrimidin-4 (3H)-one, dimedone, or 1,3-cyclohexadione and aldehydes in the presence of Fe3O4@SiO2-SnCl4 as an efficient eco-friendly catalyst under ultrasound irradiation. The final aim of this study is evaluation of antifungal activity of resulted products. | en |
| DOI | https://doi.org/10.22037/ijpr.2020.1101010 | en |
| Keyword | Pyrimido[4 | en |
| Keyword | 5-<i>b</i>]quinoline | en |
| Keyword | Antifungal activity | en |
| Keyword | Heterogeneous solid acid | en |
| Keyword | Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>-SnCl<sub>4</sub> | en |
| Keyword | Molecular modeling | en |
| Publisher | Brieflands | en |
| Title | Docking, Synthesis and Evaluation of the Antifungal Activity of Pyrimido [4,5-b]quinolins | en |
| Type | Original Article | en |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- ijpr-19-251.pdf
- Size:
- 632.8 KB
- Format:
- Adobe Portable Document Format
- Description:
- Article/s PDF