Twelve-Week Aerobic Training Decreases Chemerin Level and Improves Cardiometabolic Risk Factors in Overweight and Obese Men

AuthorAbbas Saremien
AuthorNader Shavandien
AuthorMohammad Parasteshen
AuthorHassan Daneshmanden
OrcidAbbas Saremi [0000-0002-0113-1497]en
Issued Date2010-08-31en
AbstractPurpose: The inflammatory state of adipose tissue in obese subjects may be the most important factor linking increased adipose tissue mass to insulin resistance. Chemerin is a newly discovered adipokine that plays an important role in macrophage infiltration into adipose tissue and may contribute to the development of inflammation and insulin resistance. We examined the effects of 12 weeks of aerobic training on serum chemerin levels in association with cardiovascular risk factors in overweight and obese males. Methods: Twenty-one overweight and obese subjects [44.3 (4.1 yrs, body mass index (BMI) ?25 kg/m2) were assigned to exercise training (obese EX, n= 11) and control (obese CON, n= 10) groups. The obese EX group participated in 12 weeks of progressive aerobic training 5 days a week. Serum chemerin, insulin resistance, lipid profiles, blood pressure, and body composition were all measured before and after the training. Results: After the aerobic training, waist circumference (P=0.009), fat percent (P=0.03), visceral fat (P=0.03), subcutaneous fat (P=0.01), fasting glucose (P=0.01), insulin resistance (P=0.03), triglyceride (P=0.05), total cholesterol (P=0.04), low-density lipoprotein cholesterol (P=0.05) and systolic blood pressure (P=0.04) of participates were significantly decreased. Concurrently, serum chemerin concentrations were significantly decreased after aerobic program (P=0.02). Conclusion: Aerobic training caused an improvement in cardiometabolic risk factors in obese subjects, and this improvement was accompanied by decreased chemerin levels.en
DOIhttps://doi.org/10.5812/asjsm.34860en
KeywordExerciseen
KeywordTrainingen
KeywordObesityen
KeywordMetabolic syndromeen
KeywordChemerinen
PublisherBrieflandsen
TitleTwelve-Week Aerobic Training Decreases Chemerin Level and Improves Cardiometabolic Risk Factors in Overweight and Obese Menen
TypeResearch Articleen

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