Lead exposure impairs the NMDA agonist-induced NOS expression in pyramidal hippocampal cells

AuthorSeyed Nasser Ostaden
AuthorMohammad Hossain Ghahremanien
Issued Date2006-10-31en
AbstractChronic exposure to lead (Pb) affects neural functions in central nervous system (CNS) particularly the learning and memory. On the other hand, alteration of calcium level in the CNS results in activation of NOS. It has been shown that lead enters the neurons through calcium channels and displaces Ca2+ from calcium binding proteins such as calmodulin and troponin C thereby affecting calcium-mediated processes.en
DOIhttps://doi.org/10.22037/ijpr.2010.687en
KeywordExpressionen
KeywordnNOSen
KeywordPyramidal cellen
KeywordNMDA agonisten
KeywordACBDen
KeywordLead acetateen
PublisherBrieflandsen
TitleLead exposure impairs the NMDA agonist-induced NOS expression in pyramidal hippocampal cellsen
TypeResearch Articleen

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