Simultaneous Determination of Diosmin and Hesperidin in Pharmaceuticals by RPLC using Ionic Liquids as Mobile Phase Modifiers
| Author | Marcin Szymański | en |
| Author | Daria Młynarek | en |
| Author | Arkadiusz Szymański | en |
| Author | Irena Matławska | en |
| Issued Date | 2016-01-31 | en |
| Abstract | Diosmin and hesperidin are natural flavonoid glycosides found in various plant materials, mainly in citrus fruits in different concentrations. Diosmin for pharmaceutical use is obtained mainly semi-synthetically from hesperidin. Hesperidin often accompanies diosmin as a natural impurity in different pharmaceutical formulations; therefore, a simple, fast and precise method for the simultaneous assay of diosmin and hesperidin in pharmaceutical formulations has been developed to control their contents. | en |
| DOI | https://doi.org/10.22037/ijpr.2016.1783 | en |
| Keyword | Diosmin | en |
| Keyword | Hesperidin | en |
| Keyword | Reverse-Phase Liquid Chromatography | en |
| Keyword | Ionic liquids | en |
| Publisher | Brieflands | en |
| Title | Simultaneous Determination of Diosmin and Hesperidin in Pharmaceuticals by RPLC using Ionic Liquids as Mobile Phase Modifiers | en |
| Type | Original Article | en |
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