Effect of Resistance Training on Adipose Tissue and Serum METRNL Levels in Sucrose Solution Fed Rats
| Author | Hadiseh Abdi Ziari | en |
| Author | Alireza Safarzade | en |
| Orcid | Hadiseh Abdi Ziari [0000-0002-3867-8437] | en |
| Orcid | Alireza Safarzade [0000-0002-8413-3665] | en |
| Issued Date | 2023-06-30 | en |
| Abstract | Background: Meteorin-like protein (METRNL) is a novel adipomyokine that may improve glucose tolerance, and its circulating levels are affected by changes in body weight. Objectives: This study aimed to evaluate the effects of eight weeks of resistance training (RT) and high sucrose consumption on serum and adipose tissue METRNL levels in male rats. Methods: In this study, 32 Wistar male rats were divided into normal diet and high sucrose diet groups. After 4 weeks, each group was divided into control and training groups. The rats in the training group were subjected to the RT program (3 days/week, for 8 weeks). In addition to serum and adipose tissue levels of METRNL, we measured epididymal and mesenteric fat mass, serum glucose, insulin, and homeostatic model assessment of insulin resistance (HOMA-IR). Results: High sucrose diet increased fat weights and serum levels of glucose, insulin, and IR index; nevertheless, it reduced the serum levels of METRNL. RT decreased serum insulin concentrations and HOMA-IR. The result of two-way ANOVA and the t-test showed that eight weeks of RT decreased serum levels of METRNL, insulin, and HOMA-IR in sugar solution-fed rats. Conclusions: The results suggest that RT may be an effective intervention to reduce serum METRNL and HOMA-IR levels, which is associated with improving body composition. | en |
| DOI | https://doi.org/10.5812/thrita-133670 | en |
| URI | https://brieflands.com/journals/thrita/articles/133670 | en |
| Keyword | Insulin Resistance | en |
| Keyword | Resistance Training | en |
| Keyword | Adipokines | en |
| Keyword | Adipose Tissue | en |
| Publisher | Brieflands | en |
| Title | Effect of Resistance Training on Adipose Tissue and Serum METRNL Levels in Sucrose Solution Fed Rats | en |
| Type | Research Article | en |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- thrita-12-1-133670.pdf
- Size:
- 159.32 KB
- Format:
- Adobe Portable Document Format
- Description:
- Article/s PDF