Quilty Effect: Its Definition and Significance, in Post-Cardiac Transplant Endomyocardial Biopsies with Focus on Our Experience
| Author | Kambiz Mozaffari | en |
| Author | Hooman Bakhshandeh | en |
| Author | Akbar Nikpajouh | en |
| Author | Nasim Naderi | en |
| Author | Ali Sadeghpour Tabaei | en |
| Orcid | Hooman Bakhshandeh [0000-0002-5102-1501] | en |
| Orcid | Akbar Nikpajouh [0000-0001-5625-3101] | en |
| Orcid | Nasim Naderi [0000-0001-6067-040X] | en |
| Issued Date | 2017-01-01 | en |
| Abstract | Background: The recent trend of cardiac transplantation has been dramatic in our center, thus entailing the interpretation of endomyocardial biopsies in such patients. Objectives: With this fact borne in mind, we decided to review the cases from the point of view of a certain diagnostic challenge, namely quilty lesion or effect. Methods: From April 2010 to December 2012, 42 patients with heart transplant have undergone endomyocardial biopsies and 63 samples were acquired. Results: Mean age of the patients was 30 ± 15.7 years (male/female: 34/8). Quilty effect was seen in 8 out of 63 samples (12.7%). Conclusions: The incidence of quilty lesion was within the range defined for this finding. When the lesion extends to the underlying myocardial tissue, it can be a diagnostic challenge. In the eyes of an inexperienced observer, ISHLT grade 2 rejection may be diagnosed instead of invasive quilty lesion. Therefore, experienced pathologists play an important role in this regard in all the cardiovascular transplantation sites. | en |
| DOI | https://doi.org/10.5812/mcardia.9615 | en |
| Keyword | Heart Transplantation | en |
| Keyword | Quilty Effect | en |
| Keyword | Graft Rejection | en |
| Keyword | Biopsy | en |
| Publisher | Brieflands | en |
| Title | Quilty Effect: Its Definition and Significance, in Post-Cardiac Transplant Endomyocardial Biopsies with Focus on Our Experience | en |
| Type | Brief Report | en |
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