Genotype A2/adw2 Strain of Hepatitis B Virus in Turkey
| Author | Murat Sayan | en |
| Author | Sila Cetin Akhan | en |
| Author | Mithat Bozdayi | en |
| Issued Date | 2010-12-31 | en |
| Abstract | Background and Aims: Previous studies have demonstrated the dominance of genotype D subtype ayw in patients with hepatitis B virus infection in Turkey. The aim of the present study is to report, for the first time, genotype A2 subtype adw2 of hepatitis B virus in a patient who is an inactive hepatitis B carrier in Turkey. Materials and Methods: Hepatitis B virus DNA isolated from the serum sample was amplified by polymerase chain reaction. The polymerase gene segment of the hepatitis B virus was directly sequenced. A distance matrix/UPGMA comparison was used for phylogenetic analysis, and the genotype of the virus was identified accordingly. The subgenotype and subtype of hepatitis B virus were also detected. Results: The genotyping of the patient revealed that the isolated hepatitis B virus was genotype A2/adw2. Discussion: The subtype is inconsistent with the previous data from Turkey; specifically, the identification of the A2/adw2 subtype of the hepatitis B virus in an inactive carrier is the first such case in Turkey. This finding suggests that the transmission of another genotype besides genotype D subtype ayw of the hepatitis B virus is possible in Turkey. | en |
| DOI | https://doi.org/ | en |
| Keyword | Hepatitis B virus | en |
| Keyword | Genotype | en |
| Publisher | Brieflands | en |
| Title | Genotype A2/adw2 Strain of Hepatitis B Virus in Turkey | en |
| Type | Case Report | en |
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