The Pharmacological Effects of Odonthobuthus doriae Scorpion Venom and Its Extracted Fractions on Neuro-Muscular Transmission
| Author | Amir Jalali | en |
| Author | Zahra Hossininasab | en |
| Author | Zynab Ehsani | en |
| Author | Amir-Abbas Zare | en |
| Author | Afshin Zarghi | en |
| Author | Hossein Vatanpour | en |
| Issued Date | 2006-04-30 | en |
| Abstract | The effect of Odonthobuthos doriae (O.d) scorpion venom at 0/3, 1 and 3, 10 µg/ml concentrations were investigated on nerve-muscle transmission, using the Twitch tension technique. A concentration of 0.3 µg/ml caused a small change in the twitch height in response to indirect muscle stimulation, but higher concentrations (1, 3, 10 µg/ml) caused a transient augmentation in twitch response followed by a large contracture in the chick biventer cervices (CBC) preparation. This effect could be defined as a complex action of the venom, predominately presynaptic, in which its’ effects on postjunctional synapses is also maintained. | en |
| DOI | https://doi.org/10.22037/ijpr.2010.661 | en |
| URI | https://brieflands.com/journals/ijpr/articles/128271 | en |
| Keyword | Scorpion venom | en |
| Keyword | Odonthobuthus doriae | en |
| Keyword | Pharmacological responses | en |
| Keyword | Neuro-muscular | en |
| Publisher | Brieflands | en |
| Title | The Pharmacological Effects of Odonthobuthus doriae Scorpion Venom and Its Extracted Fractions on Neuro-Muscular Transmission | en |
| Type | Research Article | en |
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