Diagnostic Value of Provocative Test by Insulin Combined with Clonidine for Growth Hormone Deficiency in Children
| Author | Cheng Guo | en |
| Author | Li Chen | en |
| Issued Date | 2013-06-30 | en |
| Abstract | Objective: To evaluate the diagnostic value of provocative test by insulin combined with clonidine for growth hormone deficiency (GHD) during childhood Methods: Eighty children underwent a provocative test with insulin(0.075U/Kg, intravenous) combined with clonidine (4μg/kg, orally). Among them, 40 children underwent clonidine provocative test, 40 children underwent insulin tolerance test (ITT) in another day. Findings: The specificity of ITT+clonidine test (74%, 88%) was remarkably higher than that of ITT (48%) or clonidine test (65%). ITT+clonidine test had a better accuracy (75%, 85%) than that of ITT (63%) or clonidine test (73%) Conclusion: We conclude that the combined clonidine+insulin test is a feasible, reliable, convenient, time saving, and safe tool for evaluation of the growth hormone (GH) axes than the clonidine test or ITT. | en |
| DOI | https://doi.org/ | en |
| Keyword | Clonidine | en |
| Keyword | Insulin | en |
| Keyword | Growth Hormone | en |
| Keyword | Growth Hormone Deficiency | en |
| Keyword | Short Stature | en |
| Publisher | Brieflands | en |
| Title | Diagnostic Value of Provocative Test by Insulin Combined with Clonidine for Growth Hormone Deficiency in Children | en |
| Type | Research Article | en |
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