Homoisoflavonoids and the Antioxidant Activity of <i>Ophiopogon japonicus</i> Root
Author | Yancui Wang | en |
Author | Feng Liu | en |
Author | Zongsuo Liang | en |
Author | Liang Peng | en |
Author | Bangqing Wang | en |
Author | Jing Yu | en |
Author | Yingying Su | en |
Author | Cunde Ma | en |
Issued Date | 2017-01-31 | en |
Abstract | The root of Ophiopogon japonicus has been used as a traditional Chinese medicine and also a functional food ingredient for a long time in China. In the present study, 17 different homoisoflavonoid compounds were identified in the root extract of O. japonicus by HPLC–DAD and LCMS/MS analyses. The antioxidant activity of the of chloroform/methanol (1:1, v/v), methanol and 70% ethanol extracts, and two major isolated homoisoflavonoid compounds (methylophiopogonanone A and methylophiopogonanone B) from O. japonicus root were investigated by various in-vitro assays. Methylophiopogonanone B showed the highest antioxidant ability according to four antioxidant methods. Among the extracts, the chloroform/methanol extract which contained high amounts of homoisoflavonoids was found to exhibit the strongest antioxidant activity. The results showed that O. japonicus root can be regarded as a potential source of homoisoflavonoids and natural antioxidant. | en |
DOI | https://doi.org/10.22037/ijpr.2017.1979 | en |
Keyword | <i>Ophiopogon japonicas</i> | en |
Keyword | Homoisoflavonoids | en |
Keyword | LCMS/MS analysis | en |
Keyword | Antioxidant activity | en |
Publisher | Brieflands | en |
Title | Homoisoflavonoids and the Antioxidant Activity of <i>Ophiopogon japonicus</i> Root | en |
Type | Original Article | en |
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