Homoisoflavonoids and the Antioxidant Activity of <i>Ophiopogon japonicus</i> Root

AuthorYancui Wangen
AuthorFeng Liuen
AuthorZongsuo Liangen
AuthorLiang Pengen
AuthorBangqing Wangen
AuthorJing Yuen
AuthorYingying Suen
AuthorCunde Maen
Issued Date2017-01-31en
AbstractThe root of Ophiopogon japonicus has been used as a traditional Chinese medicine and also a functional food ingredient for a long time in China. In the present study, 17 different homoisoflavonoid compounds were identified in the root extract of O. japonicus by HPLC–DAD and LCMS/MS analyses. The antioxidant activity of the of chloroform/methanol (1:1, v/v), methanol and 70% ethanol extracts, and two major isolated homoisoflavonoid compounds (methylophiopogonanone A and methylophiopogonanone B) from O. japonicus root were investigated by various in-vitro assays. Methylophiopogonanone B showed the highest antioxidant ability according to four antioxidant methods. Among the extracts, the chloroform/methanol extract which contained high amounts of homoisoflavonoids was found to exhibit the strongest antioxidant activity. The results showed that O. japonicus root can be regarded as a potential source of homoisoflavonoids and natural antioxidant.en
DOIhttps://doi.org/10.22037/ijpr.2017.1979en
Keyword<i>Ophiopogon japonicas</i>en
KeywordHomoisoflavonoidsen
KeywordLCMS/MS analysisen
KeywordAntioxidant activityen
PublisherBrieflandsen
TitleHomoisoflavonoids and the Antioxidant Activity of <i>Ophiopogon japonicus</i> Rooten
TypeOriginal Articleen

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