Atopic Manifestations: Dermatitis, Allergic Rhinitis and Asthma in Patients With Hypogammaglobulinemia
| Author | Minoo Dadkhah | en |
| Author | Asghar Aghamohammadi | en |
| Author | Masoud Movahedi | en |
| Author | Mohammad Gharagozlou | en |
| Issued Date | 2015-10-28 | en |
| Abstract | Background:: Most of the hypogammaglobulinemic patients have a clinical history in favor of allergic respiratory disease. Nevertheless, in these patients the importance and prevalence of atopic disorders have not been completely explained. Objectives:: This study was aimed to evaluate atopic manifestations (dermatitis, allergic rhinitis and asthma) and pulmonary function in patients with hypogammaglobulinemia. Patients and Methods:: We used the international study of asthma and allergies in childhood (ISAAC) questionnaire in forty-five patients diagnosed with hypogammaglobulinemia and spirometry was done in 41 patients older than 5 years. Results:: Spirometry results were normal in 21 (51%), and showed obstructive in 15 (37%) and restrictive pattern in 5 (12%) of the 41 patients who were evaluated. By the end of the study, asthma was diagnosed in nine (20%) patients and other atopies (rhinitis and dermatitis) identified in 10 (22%), and four (9%), respectively. Conclusions:: Atopic conditions should be investigated in the hypogammaglobulinemic patients and the prevalence in these patients may be higher than in normal population. Also, it is recommended to perform a pulmonary function test as a routine procedure in patients with hypogammaglobulinemia and atopy should be assessed in these patients. | en |
| DOI | https://doi.org/10.5812/ijp.2786 | en |
| Keyword | Allergic Rhinitis | en |
| Keyword | Asthma | en |
| Keyword | Atopic Dermatitis | en |
| Keyword | FEV<sub>1</sub> | en |
| Keyword | Immunodeficiency | en |
| Publisher | Brieflands | en |
| Title | Atopic Manifestations: Dermatitis, Allergic Rhinitis and Asthma in Patients With Hypogammaglobulinemia | en |
| Type | Research Article | en |
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