Fulminant Myocarditis Complicated with Immune Checkpoint Inhibitor in Patients with Thymoma: Report of Three Cases

AuthorDaozheng Huangen
AuthorFeier Songen
AuthorWeidai Zhangen
AuthorHuan Maen
AuthorXingtao Linen
AuthorTiehe Qinen
AuthorShouhong Wangen
Issued Date2022-06-30en
AbstractImmune checkpoint inhibitors (ICIs) prevent the immune escape of tumor cells, which helps immune cells such as T lymphocytes to continuously monitor and kill tumor cells, and play powerful anti-tumor role. Immune checkpoint inhibitor-associated myocarditis has been rarely reported; however, its latent, rapidly developed, and lethal onset has gradually attracted the attention of clinicians. This study aimed to report cases of fulminant myocarditis in three patients with thymoma who were treated with pembrolizumab, one of the programmed cell death protein 1 inhibitors (PD-1 inhibitors).en
DOIhttps://doi.org/10.5812/intjcardiovascpract-130990en
KeywordProgrammed Cell Death Protein 1 Inhibitoren
KeywordPd-1 Inhibitoren
KeywordImmune Checkpoint Inhibitorsen
KeywordMyocarditisen
KeywordThymomaen
PublisherBrieflandsen
TitleFulminant Myocarditis Complicated with Immune Checkpoint Inhibitor in Patients with Thymoma: Report of Three Casesen
TypeCase Reporten

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