Brieflands

History

The company was first founded by Seyyed M. Miri and Seyed-M Alavian as an editorial group in a Medical Institute in 2007 to publish its medical journal. After three years of experience, the number of journals increased to 5 journals, and the company launched its first form of business as a VOF (collaboration) professional STM company in Heerlen, the Netherlands, which was called "Kowsarmedical Publishing." Respecting the publishing services (from submission to publishing), especially an in-house "Journal Management System," our journals increased to more than 60 STM journals between 2010 and 2019. Since 2022, "Brieflands" is the new brand name that acts as a "Science, Technical, Medical Publisher" that publishes more than 50 journals with the services provided by 97 expert employees in three different branches.

Business Profile

  • Brieflands is a Registered Trademark with record number 1454012.
  • Brieflands has been registered as a General partnership (Vennootschap onder firma) company in the Chamber of Commerce (Kamer van Koophandel) of the Netherlands since 2010.
  • Nedmedica is our related company which is specialized in Author Services. 
  • Our former branding name was Kowsarmedical Publishing (2010-2021).
 

Communities in Brieflands

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Recent Submissions

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Integrative Network Analysis of Bioactive Compounds from Punica granatum L. Peel: Multi-Target Mechanisms in Wound Healing
(Brieflands, 2026-12-31) Seyyed Shahab Shokri; Ebrahim Salimi Sabour; Seyed Morteza Hosseini; Hossein Reza Shateri; Seyyed Shahab Shokri [0009-0006-5735-6173]; Ebrahim Salimi Sabour [0000-0002-5315-2126]; Seyed Morteza Hosseini [0000-0001-9987-3829]; Hossein Reza Shateri [0009-0002-1580-686X]
Background: Wound-healing agents often have limited efficacy and require prolonged recovery times, prompting growing interest in developing herbal-based formulations. Among these, Punica granatum L. has attracted considerable attention because of its high polyphenolic content. Despite its widespread use, the precise pharmacological targets underlying its wound-healing effects remain poorly understood and require systematic investigation. Objectives: This study aimed to elucidate the underlying pharmacological mechanisms of the topical wound-healing properties of P. granatum L. using a network pharmacology approach. Methods: Bioactive compounds of P. granatum L. and their potential target genes were identified using the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP), Similarity Ensemble Approach (SEA), and SwissTargetPrediction databases. Wound healing-related genes were retrieved from the GeneCards database. Genes intersecting P. granatum L. targets and wound healing-associated genes were subjected to functional enrichment analyses, including protein–protein interaction (PPI), Gene Ontology (GO), and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses. The PPI network was further analyzed using Cytoscape, and the phytoconstituent–target interaction network was visualized using Gephi. These findings were validated using molecular docking. Results: A total of 40 intersecting genes were identified as potential P. granatum L. targets involved in wound healing. Among these, EGFR, PTPN11, HRAS, IGF1R, and ESR1 were identified as key hub genes. Functional enrichment analysis indicated that the most significantly enriched signaling pathways included the MAPK, PI3K-Akt, EGFR tyrosine kinase inhibitor resistance, focal adhesion, and FoxO signaling pathways. Molecular docking analysis confirmed favorable binding of quercetin and ellagic acid to the hub targets EGFR, IGF1R, and ESR1. Conclusions: These findings elucidate the pharmacological pathways underlying P. granatum-mediated wound healing and suggest that P. granatum L. acts as a multi-target modulator in the wound-healing process.
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Beyond Decontamination: Family-Centered Psychosocial Consequences of CBRN Events
(Brieflands, 2026-09-30) Sajjad Narimani; Hesam Seyedin; Shandiz Moslehi; Asghar Tavan; Sajjad Narimani [0000-0001-7026-9951]; Shandiz Moslehi [0000-0003-3099-0626]; Asghar Tavan [0000-0002-1090-2214]
Context: Chemical, biological, radiological, and nuclear (CBRN) crises have traditionally been addressed through technical and biomedical responses, such as detection and decontamination. However, these frameworks largely overlook the profound psychosocial effects on families, which are the primary units of care and resilience. The invisible and ambiguous nature of CBRN events uniquely destabilizes intimate relationships and domestic life. Evidence Acquisition: This conceptual commentary is based on a narrative synthesis of cross-disciplinary insights from disaster psychology, crisis sociology, and existing psychosocial care guidelines. It examines the distinctive features of CBRN events, such as invisibility and uncertainty, and applies this framework to intrafamilial dynamics, supported by evidence from related fields, including pandemic psychology and case studies from past CBRN events. Results: The analysis identifies key mechanisms through which CBRN events fracture family resilience: 1) contamination anxiety transforms protective caregiving into policed interactions, stifling spontaneity; 2) the suppression of physical touch, a primary channel for safety and belonging, leads to emotional isolation; 3) shared family narratives fragment into individualized ontologies of risk, eroding trust and the collective “we”; and 4) internal role conflicts and boundary retractions further weaken domestic bonds. These dynamics are particularly pronounced in cultural contexts such as Iran, where familial closeness and shared rituals are central to social life. Conclusions: A holistic and humane CBRN preparedness paradigm must extend beyond biomedical survival and technical decontamination to actively protect and restore family relationships. True resilience should be measured by the restoration of trust, affection, and collective belonging within households. Emergency management should therefore integrate family-centered psychosocial support, train responders in relational dynamics, and develop communication strategies that sustain cohesion, with the ultimate goal of restoring not only lives but also the relational fabric of society.
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The Relationship Between Psychological Well-Being and Mental Health with Self-esteem and Social Adjustment in Children Under Welfare Organization Care: A Study in Pediatric Health Psychology
(Brieflands, 2026-04-30) Nilofar Rafie; Seyed Ali Majidi; Seyedeh Maryam Mousavi
Background: Institutionalized children often face significant emotional and social challenges due to early life adversity. Understanding the psychological determinants of their well-being is essential for effective interventions in health psychology and child welfare. Objectives: The aim of this study, evaluation of relationship between psychological well-being and mental health with Self-esteem and social adjustment in children under the care of the Iranian Welfare Organization. Methods: A descriptive-correlational study was conducted on 152 children (both boys and girls) living in welfare centers in Rasht, Iran, in 2025. Participants were selected using Cochran’s sample size formula and convenience sampling. Data were collected using validated tools: Coopersmith’s Self-esteem Inventory (1967), Sinha and Singh’s Social Adjustment Scale (1973), Paloutzian and Ellison’s Psychological Well-Being Scale (2002), and Besharat’s Mental Health Scale (2009). Finally, multiple regression analyses were performed using SPSS version 24. Results: The findings revealed significant positive correlations between psychological well-being and both Self-esteem (β = 0.37, p < 0.01) and social adjustment (β = 0.42, p < 0.01). Similarly, mental health was positively associated with Self-esteem (β = 0.34, p < 0.01) and social adjustment (β = 0.39, p < 0.01). Regression analysis demonstrated that psychological well-being explained 27% of the variance in social adjustment and 23% in self-esteem, while mental health accounted for 21% and 19% of the variance in social adjustment and self-esteem, respectively. These results indicate that both psychological well-being and mental health are significant predictors of emotional and social functioning in institutionalized children. Conclusions: Psychological well-being and mental health are critical components influencing the Self-esteem and social integration of children in institutional care. Enhancing these variables through targeted psychological interventions may improve long-term mental health outcomes in this vulnerable population.
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The Relationship Between Media Usage and Sleep in Healthy Children Aged 6 - 11 Years
(Brieflands, 2026-04-30) Feyza Yucel Yilmaz; Bahar Cuhaci Cakir; Nazmi Mutlu Karakas; Aysu Duyan Camurdan
Background: The use of media tools among children and the time spent in front of media tools are increasing. In addition to the positive effects of digital media tools, negative effects such as sleep disorders, obesity, learning and attention deficits worry both families and physicians. Objectives: This study aimed to investigate the correlation between media usage and sleep patterns among healthy children aged 6 to 11 years. Methods: This survey was conducted as an observational cross-sectional study at the outpatient clinics of the Division of Social Pediatrics and General Pediatrics of Gazi University Faculty of Medicine. This study includes a total of 287 children aged 6 - 11 years who were admitted to the hospital during the study period between March and May 2023. Two validated scales were used: the 9-item Problematic Media Use Measure-Short Form and the 26-item Sleep Disturbance Scale for Children. Results: The mean age of the 287 children was 8.5 ± 1.5 years. Nearly half of them (48%) began using digital media before 24 months of age. Forty-two percent had screen exposure within 30 minutes of bedtime. While the mean score of the Problematic Media Use Measure-Short Form was 2.40 ± 0.86, the mean score of the Sleep Disturbance Scale for children was found to be 45.2 ± 10.3. Higher scores indicate a greater level of problematic media use in the child. Sleep disturbance was reported in 15% of the participants. Higher problematic media use scores correlated with greater sleep disturbance. Those who began media use before 24 months demonstrated higher sleep disturbance scores. Scores were also high with gaming, particularly violent war games. Media use for war games increased the problematic media use score by 4.1 times, screen exposure within one hour before bedtime increased the score by 3.1 times, and spending more than 2 hours in front of the computer increased the score by 4.8 times. Moreover, spending 2 hours or more in front of a cell phone increased the sleep disturbance score by 2.8 times. Conclusions: This study revealed an association between increased problematic media use and higher rates of sleep disturbances in children aged 6 - 11 years. Since the cross-sectional study design did not allow us to draw definitive conclusions, more longitudinal studies are needed to investigate the risks associated with screen time behaviors.
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Barriers and Facilitators to Shared Decision-Making on Venous Access in Childhood Cancer: A Multi-perspective Qualitative Study
(Brieflands, 2026-04-30) Zhenzhen Huang; Xu Hong Zhen; Midan Zhang; Changpian Bi; Meifang Xu; Qin Wang
Background: Childhood cancers, though relatively rare, are a leading cause of disease-related death in children. Chemotherapy, which requires central venous access devices [peripherally inserted central catheters (PICCs)or implantable venous access ports (PORTs)], is fundamental. However, the child’s perspective is often overlooked in device selection. Objectives: This study aims to understand the current status and influencing factors of shared decision-making (SDM) regarding venous access selection from the perspectives of children with cancer and their parents and to explore the facilitators and barriers to children’s participation in SDM, so as to provide evidence for promoting pediatric involvement in clinical decision-making. Methods: A qualitative interview study was conducted using purposive sampling. Twelve children hospitalized in hematology and oncology departments and 14 parents were recruited between May and July 2025. Semi-structured interviews were performed, and the data were analyzed using a grounded theory (GT) approach for coding, category development, and theme extraction. Results: Children’s participation in SDM was influenced by multiple interacting factors. Insufficient information; limited communication with parents or physicians; concerns about decision outcomes; and fear of pain or discomfort led children to adopt passive acceptance or indifference. Conversely, desires for more information, respect, and being heard motivated active engagement. Children’s preferred decision-making approaches varied, including parent-led, physician-led, and shared models. Parental perceptions of their child’s age, maturity, and decision-making capacity directly determined whether they supported the child’s involvement. These perceptions shaped parents’ attitudes, ranging from protective to autonomy-supporting, which in turn influenced their chosen decision-making approach and ultimately determined whether children were genuinely included in the process. Conclusions: This study reveals that SDM regarding venous access in children with cancer is a complex process shaped by the interplay of child, parent, and clinical factors. Although children express a desire to participate, their preferred level of involvement varies and is often limited by information gaps, communication barriers, and psychological concerns. Parental attitudes critically influence whether children are genuinely included. By capturing the perspectives of both children and parents, this study identifies key barriers and facilitators, offering a foundation for developing inclusive, age-appropriate SDM models and communication strategies in pediatric oncology practice and future research.