Brieflands

History

The company was first founded by Seyyed M. Miri and Seyed-M Alavian as an editorial group in a Medical Institute in 2007 to publish its medical journal. After three years of experience, the number of journals increased to 5 journals, and the company launched its first form of business as a VOF (collaboration) professional STM company in Heerlen, the Netherlands, which was called "Kowsarmedical Publishing." Respecting the publishing services (from submission to publishing), especially an in-house "Journal Management System," our journals increased to more than 60 STM journals between 2010 and 2019. Since 2022, "Brieflands" is the new brand name that acts as a "Science, Technical, Medical Publisher" that publishes more than 50 journals with the services provided by 97 expert employees in three different branches.

Business Profile

Brieflands is a Registered Trademark with record number 1454012.
Brieflands has been registered as a General partnership (Vennootschap onder firma) company in the Chamber of Commerce (Kamer van Koophandel) of the Netherlands since 2010.
- KvK number: 89235444.
- BTW (VAT) number: NL864918896B01 (check online at VIES )
- RSIN: 864918896
Nedmedica is our related company which is specialized in Author Services.
Our former branding name was Kowsarmedical Publishing (2010-2021).

Communities in Brieflands

Select a community to browse its collections.

Recent Submissions

Explaining the Long-Term Effects of COVID-19 on Spiritual Health in Individuals with a History of Hospitalization Due to Coronavirus Infection
(Brieflands, 2026-12-31)
Atieh Ebrahimian
;
Melika Kharghani Moghadam
;
Morteza Mansourian
;
Bagher Ghobari Bonab
;
Fatemeh Gholami
Background: Hospitalization for COVID-19 has been associated with profound psychological, social, and spiritual consequences that may persist long after physical recovery. Although previous studies have examined the immediate spiritual impact of COVID-19, few have explored how spiritual experiences evolve over time among individuals hospitalized for the disease. Understanding these long-term experiences is essential to developing holistic recovery programs that address spiritual well-being alongside physical and psychological health. Objectives: This study aimed to explore the long-term effects of COVID-19 on the spiritual health of individuals with a history of hospitalization for coronavirus infection. Methods: This longitudinal qualitative study used conventional qualitative content analysis to explore the spiritual experiences of individuals hospitalized with COVID-19 over a four-year period. Participants were selected through purposive sampling to ensure variation in age, gender, educational level, and illness severity. Initially, 120 participants were recruited, and annual follow-up interviews were conducted; 86 participants completed the fourth-year interview. Data were collected through semistructured, in-depth interviews at four time points. Longitudinal analysis involved comparing participants’ narratives across interview waves to identify continuity, change, and transformation in spiritual experiences over time. Data were analyzed through systematic coding, categorization, and theme development. Trustworthiness was established using Lincoln and Guba’s criteria of credibility, transferability, dependability, and confirmability. Results: The analysis revealed five interconnected themes reflecting the evolving nature of spiritual experiences following COVID-19 hospitalization. Participants described changes in spiritual beliefs, experiences of uncertainty and spiritual struggle, processes of meaning reconstruction, and the development of coping strategies throughout the four-year follow-up period. Longitudinal comparisons indicated that participants’ spiritual experiences were dynamic and nonlinear. Early narratives often involved fear, vulnerability, and questioning, whereas later accounts frequently reflected adaptation, reinterpretation of illness experiences, and renewed perspectives on life purpose. Participants described spiritual practices and reflection as meaningful resources during recovery and emphasized the importance of family, community, and spiritual connections in restoring a sense of belonging. For some participants, long-term integration of the illness experience was associated with perceived spiritual growth, strengthened values, and a deeper sense of meaning, although these experiences varied among individuals. Conclusions: The findings suggest that hospitalization for COVID-19 may have lasting effects on spiritual health that extend well beyond physical recovery. Participants’ experiences indicate that spiritual health is not static but evolves through a longitudinal process of crisis, reflection, adaptation, and growth. These changes influenced participants’ relationships with themselves, others, and God and contributed to their psychological and social recovery. The findings highlight the importance of integrating spiritual care into long-term post-COVID support services and recovery programs.
Comparing the Effects of Laughter Therapy and Cognitive Behavioral Therapy on Mental Ealth and Hopefulness in Pakistani Dialysis Patients
(Brieflands, 2026-10-31)
Muhammad Azam
;
Muhammad Sabir
;
Waseem Abbas
;
Zobia Akram
;
Shima Sadat Aghahosseini
Background: Chronic renal failure often requires dialysis as a life-sustaining treatment. However, dialysis is frequently associated with psychological complications, including stress, depression, and hopelessness. Objectives: This study aimed to compare the effects of laughter therapy and cognitive behavioral therapy on mental health and hopefulness in Pakistani patients undergoing dialysis. Methods: A total of 145 patients meeting the inclusion criteria were enrolled in a quasi-experimental study using convenience sampling at teaching hospitals in Lahore. Participants were allocated to three groups: laughter therapy (LT; n = 48), cognitive behavioral therapy (CBT; n = 48), and control (n = 49). The interventions comprised eight 1-hour sessions. Data were collected using a demographic questionnaire, the Symptom Checklist-90-Revised (SCL-90-R), and the Snyder Hope Scale (SHS) at baseline, immediately after the intervention, and at the 3-month follow-up. A total of 135 participants completed the post-intervention assessment, and 121 completed the 3-month follow-up and were included in the final complete-case analysis. Results: There were no statistically significant differences in baseline demographic characteristics among the three groups (P > 0.05). The mean ages in the LT, CBT, and control groups were 48.11 ± 13.56, 49.00 ± 13.14, and 48.30 ± 13.38 years, respectively. Significant time × group interactions were observed for psychological symptom severity (F = 12.714, P < 0.001, ηp2 = 0.300) and hopefulness (F = 8.563, P < 0.001, ηp2 = 0.224). Psychological symptom severity decreased from 1.82 ± 0.23 to 1.67 ± 0.49 in the LT group and from 1.84 ± 0.21 to 1.62 ± 0.48 in the CBT group, whereas hopefulness increased from 37.22 ± 2.53 to 42.82 ± 4.63 and from 39.84 ± 3.13 to 42.40 ± 5.36, respectively. The control group did not show comparable improvements. These effects were generally maintained at the 3-month follow-up. Conclusions: Laughter therapy and cognitive behavioral therapy may help reduce psychological symptom severity and improve hopefulness in patients undergoing dialysis. The favorable effects of both interventions were generally maintained at the 3-month follow-up, supporting their potential use as complementary psychological interventions in dialysis care.
Lower Serum Kindlin-2 Levels Are Associated with Liver Cirrhosis: A Preliminary Study
(Brieflands, 2026-12-31)
Özgür Altun
;
Olga Metin
;
Yucel Arman
;
Şengul Aydın Yoldemir
;
Okan Dikker
Background: Kindlin-2 is a focal adhesion protein involved in cell-cell and cell-extracellular matrix adhesion. These functions influence cell behavior and processes such as fibrosis. Kindlin-2 has recently been reported to play important roles in fibrotic diseases. Objectives: This study aimed to assess the association between serum kindlin-2 levels and liver cirrhosis. Methods: The study included 48 individuals with liver cirrhosis and 40 healthy controls. Serum kindlin-2 levels were measured using an enzyme-linked immunosorbent assay (ELISA). Complete blood count parameters and liver function tests were assessed. Liver fibrosis was evaluated using noninvasive indices, including the aspartate aminotransferase-to-platelet ratio index (APRI) and fibrosis-4 (FIB-4) index. Mortality risk was evaluated using the Model for End-Stage Liver Disease-Sodium (MELD-Na) score. Results: Serum kindlin-2 levels were lower in the liver cirrhosis group (P = 0.014). Kindlin-2 levels were inversely associated with alanine aminotransferase (ALT), aspartate aminotransferase (AST), and aminotransferase-to-platelet ratio index (APRI) scores and positively associated with platelet count. Low kindlin-2 levels were independently associated with liver cirrhosis. Conclusions: Low serum kindlin-2 levels were associated with liver cirrhosis. Correlations were observed between kindlin-2 levels and markers of liver fibrosis, as well as certain liver function tests. These findings may be a consequence of the cirrhosis process.
A Bibliometric and Content Analysis of Health Scope (2012 - 2026): Authorship, Research Methods, Thematic Scope, and Citation Patterns
(Brieflands, 2026-11-30)
Saeid Ebrahimi
;
Fatemeh Setoodehzadeh
;
Mohammad Khammarnia
;
Saeid Ebrahimi [0000-0001-5446-5944]
;
Fatemeh Setoodehzadeh [0000-0003-2749-4947]
Background: Bibliometric and content analyses are valuable approaches for evaluating journal performance and identifying publication trends. Objectives: This study examined publication, authorship, methodological, thematic, and citation patterns in Health Scope from 2012 through January 2026. Methods: This descriptive bibliometric and content-analysis study was conducted in 2026. A total of 625 records were identified from the journal archive; one retracted article was excluded, leaving 624 records for Phase I bibliometric and citation analyses. In Phase II, 513 original research articles were included in the detailed content analysis. Data were extracted using a structured checklist and summarized using descriptive statistics. Results: A total of 2,703 authors contributed to 624 published articles; 1,756 were male (65.0%). Articles with four authors were the most common (24.7%). Male researchers served as corresponding authors in 429 articles (68.8%) and as first authors in 385 articles (61.6%). Authors affiliated with Iranian institutions contributed most of the publications (567 articles, 90.9%). Environmental health was the most frequently represented thematic category (n = 131, 21.0%). Fourteen articles related to COVID-19 were published during this period. Cross-sectional studies were the most common study design (n = 212, 34.0%). Laboratory and instrumental measurements were the most frequently used data-collection methods among original research articles (n = 273, 53.2%). Clinical or hospital settings were reported in 134 of the 513 articles with available setting information (26.1%). Authors addressed empirical and population gaps in 455 and 402 articles, respectively. Through February 20, 2026, the journal received 3,169 Web of Science citations and 4,100 Scopus citations. Environmental health accounted for the largest share of citations (n = 1,303, 41.1%). Content analysis based on the United Nations 2030 Agenda framework showed that most published articles aligned with the Sustainable Development Goals (SDGs), predominantly SDG 3 (Good Health and Well-being). Conclusions: The annual publication volume remained relatively stable over the observed period. The published output encompassed diverse domains aligned with the journal's scope. Strategies to broaden international author participation should be prioritized. Strengthening methodological rigor and addressing underrepresented research gaps will further enhance publication quality.
Development of a Predictive Model for Early Death in Metastatic Hepatocellular Carcinoma Based on the SEER Database
(Brieflands, 2026-12-31)
Weiguo Liu
;
Moli Chen
;
Xue Wei
;
Peng Wang
Background: Hepatocellular carcinoma (HCC) often has an insidious onset and high metastatic potential. Early death, defined as death within 3 months of initial diagnosis, is common in metastatic HCC (mHCC). However, few studies have used current staging systems to predict this outcome. Objectives: This study aimed to develop and internally validate a predictive model for early death in mHCC (American Joint Committee on Cancer [AJCC], 8th edition, M1 stage IVB) using the Surveillance, Epidemiology, and End Results (SEER) database and to construct a nomogram for individual risk estimation. Methods: Data from patients diagnosed with metastatic HCC between 2018 and 2023 were extracted from the SEER database (version 9.0.43.0). A total of 5,877 patients were randomly divided into training (n = 4,114) and validation (n = 1,763) cohorts at a ratio of 7:3. Univariable and multivariable logistic regression analyses were performed to identify predictors. A nomogram was subsequently constructed, and its performance was evaluated using the concordance index (C-index), calibration curves, receiver operating characteristic (ROC) curves, and decision curve analysis (DCA). Results: The early death rate was 62.5% in the training cohort and 63.4% in the validation cohort. The final multivariable model retained nine predictors: age, tumor size, alpha-fetoprotein (AFP), bone metastasis, brain metastasis, lung metastasis, marital status, radiotherapy, and chemotherapy. The nomogram achieved a C-index of 0.740 in the training cohort and 0.746 in the validation cohort, outperforming the conventional tumor-node-metastasis (TNM) staging system (C-index: 0.531). Calibration curves demonstrated close agreement between predicted and observed outcomes, and decision curve analysis (DCA) indicated net clinical benefit. A reduced model excluding radiotherapy and chemotherapy had a validation C-index of 0.605. Conclusions: This SEER-based nomogram integrates nine readily available clinical variables to predict early death in patients with mHCC and demonstrates robust discrimination, calibration, and clinical utility. It provides an intuitive quantitative tool to identify high-risk patients and guide individualized treatment and follow-up strategies.