Brieflands
History
The company was first founded by Seyyed M. Miri and Seyed-M Alavian as an editorial group in a Medical Institute in 2007 to publish its medical journal. After three years of experience, the number of journals increased to 5 journals, and the company launched its first form of business as a VOF (collaboration) professional STM company in Heerlen, the Netherlands, which was called "Kowsarmedical Publishing." Respecting the publishing services (from submission to publishing), especially an in-house "Journal Management System," our journals increased to more than 60 STM journals between 2010 and 2019. Since 2022, "Brieflands" is the new brand name that acts as a "Science, Technical, Medical Publisher" that publishes more than 50 journals with the services provided by 97 expert employees in three different branches.
Business Profile
- Brieflands is a Registered Trademark with record number 1454012.
- Brieflands has been registered as a General partnership (Vennootschap onder firma) company in the Chamber of Commerce (Kamer van Koophandel) of the Netherlands since 2010.
- KvK number: 89235444.
- BTW (VAT) number: NL864918896B01 (check online at VIES)
- RSIN: 864918896
- Nedmedica is our related company which is specialized in Author Services.
- Our former branding name was Kowsarmedical Publishing (2010-2021).
Communities in Brieflands
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Recent Submissions
Match Activity Analysis in U15-U17 Elite Iranian Soccer Players
(Brieflands, 2025-12-31) Seyd Ali Hosseini; Kia Ranjbar; Sadegh Amani Shalamzari; Kia Ranjbar [0009-0006-1214-3668]; Sadegh Amani Shalamzari [0000-0002-3021-8970]
Background: Understanding age-related differences in match demands is crucial for player development in youth soccer. Although physical and physiological improvements with age are well documented, how these changes translate into match behavior, particularly in terms of running performance and acceleration-deceleration actions, remains unclear. Objectives: This study aimed to compare the physical match demands of elite U15 and U17 players, with a particular focus on speed-zone running metrics and acceleration–deceleration profiles. Methods: Sixty-two highly trained male youth soccer players (U15: n = 30; U17: n = 32) were included in the study. Match activity was monitored using 10-Hz GPS units across 12 official full-length matches (six per age group). When players participated in more than one match, data from the match in which each player recorded the greatest distance were selected for analysis. To ensure data reliability, only players who completed the full 90 minutes were included, resulting in 62 match observations. Match metrics included total distance, distance covered within standardized speed zones, and the frequency of accelerations and decelerations across four intensity categories. All variables were normalized to meters per minute to account for differences in playing time. For group comparisons, independent t-tests were conducted, and Cohen's d was calculated to estimate effect sizes. Results: U15 players covered significantly greater total distance (9742.4 ± 1269.6 m vs. 8434.5 ± 775.2 m; P < 0.001) and distance per minute (103.64 ± 13.51 vs. 89.73 ± 8.25 m·min-1; P < 0.001), primarily due to higher volumes of low-intensity running (jogging). In contrast, U17 players demonstrated a superior capacity for high-intensity mechanical actions, performing significantly more high-intensity accelerations (≥ 3 m·s-2; P = 0.001) and high-intensity decelerations (≤ −3 m·s-2; P < 0.001). No significant differences were observed between groups in high-speed running or sprinting distances. Conclusions: Age-related progression in elite youth soccer is characterized not by an increase in running volume but by a qualitative shift toward more explosive and tactically meaningful actions. Older players exhibit greater high-intensity acceleration and deceleration capacity, whereas younger players rely more on continuous low-intensity running. These findings underscore the importance of integrating neuromuscular development and tactical education into age-specific training programs to prepare players for the evolving demands of competition.
The Impact of Oral Sildenafil on Retinopathy of Prematurity in Very Preterm Newborns With Early-Onset Pulmonary Hypertension: A Retrospective Cohort Study
(Brieflands, 2026-05-31) Niloofar Nouhi; Setareh Sagheb; Kourosh Sadeghi; Sina Azadnajafabad; Ziba Mosayebi; Ameneh Lamsehchi; Setareh Sagheb [0000-0003-3298-2128]; Sina Azadnajafabad [0000-0003-0105-3801]; Ziba Mosayebi [0000-0002-1624-6967]; Ameneh Lamsehchi [0000-0002-0450-2003]
Background: Sildenafil, a phosphodiesterase type 5 inhibitor, is increasingly used in neonatal intensive care units (NICUs) to treat pulmonary arterial hypertension in preterm infants. Objectives: This study aimed to evaluate whether oral sildenafil therapy in very preterm infants with early-onset pulmonary hypertension is associated with the development of retinopathy of prematurity, particularly treatment-requiring (type 1) retinopathy of prematurity. Methods: We conducted a retrospective cohort study of preterm neonates with a gestational age ≤ 31 weeks and early-onset pulmonary hypertension who were admitted to 2 tertiary NICUs in Tehran between 2017 and 2022. Infants who received oral sildenafil comprised the exposed group, and those managed without sildenafil comprised the unexposed group. Retinopathy of prematurity screening was performed according to national guidelines. Univariable and multivariable Poisson regression models were used to estimate crude and adjusted risk ratios for treatment-requiring (type 1) retinopathy of prematurity. Results: Of 303 screened neonates, 74 met the inclusion criteria, including 38 sildenafil-exposed infants and 36 unexposed infants. The mean (SD) gestational age was 28.5 ± 1.5 weeks. The overall incidence of retinopathy of prematurity did not differ significantly between the sildenafil-exposed and unexposed groups (68.6% vs 72.2%; P = 0.700). Treatment-requiring retinopathy of prematurity occurred in 26.5% of infants in the sildenafil-exposed group and 27.8% of infants in the unexposed group, with no significant difference between groups (P > 0.99). The incidence of stage 3 retinopathy of prematurity was also similar between groups (8.6% vs 11.1%; P = 0.800). Univariable analysis showed no association between sildenafil exposure and retinopathy of prematurity (crude risk ratio, 0.95; 95% CI, 0.70 - 1.29; P = 0.740), and this association remained nonsignificant after adjustment for relevant clinical covariates (adjusted risk ratio, 1.04; 95% CI, 0.70 - 1.55; P = 0.840). Conclusions: Early oral sildenafil therapy was not associated with an increased risk of severe retinopathy of prematurity or treatment-requiring retinopathy of prematurity in very preterm infants. Larger prospective studies are warranted to confirm its ocular safety.
Comparison of Esophagography and Chest Computed Tomography and the Prognostic Value of Inflammatory Markers for Detecting Anastomotic Leakage After Esophageal Resection
(Brieflands, 2026-03-31) Seyed Hosein Mirjavadi; Mohadese Estaji; Soheila Koopaee; Farideh Pak; Amirmohsen Jalaeefar; Elahe Jazayeri Gharehbagh; Soheila Koopaee [0000-0002-0883-438X]
Background: Esophageal cancer poses substantial treatment challenges, particularly when esophagectomy is required. Despite advances in multimodality therapy, esophagectomy remains the primary curative approach. Anastomotic leakage (AL) after esophagectomy is associated with mortality rates of up to 40%–60%. Therefore, timely detection and intervention are essential to mitigate adverse outcomes. Objectives: This study aimed to identify the gold standard for assessing AL after esophageal resection. Methods: This prospective study was conducted at Imam Khomeini Complex Hospital, Tehran, Iran. From May to December 2022, a total of 46 patients who underwent esophageal or gastric resection for cancer were enrolled. Patients were evaluated using esophagography, chest computed tomography (CT), C-reactive protein (CRP) levels on postoperative days (within 30 days, as the gold standard of care), and clinical signs. Thirty patients underwent postoperative radiographic examination using a water-soluble contrast medium, and 16 underwent chest CT with oral and intravenous contrast medium during the same period. CRP levels were measured in all patients on the day of esophagography or chest CT. Results: Ten patients exhibited clinical signs of leakage. Among the 30 patients who underwent radiographic examination, 27 (90%) had normal findings and 3 (10%) had AL, whereas clinical signs of AL were present in 10 patients (33.3%). Among the 16 patients who underwent chest CT, 9 (56.3%) had normal findings and 7 (43.8%) had AL. The sensitivity, specificity, and accuracy of radiographic examination were 30%, 100%, and 71.43%, respectively, compared with 71.43%, 66.67%, and 68.75%, respectively, for chest CT. The chi-square test showed no association between CRP levels and clinical signs of leakage (P = 0.771). Conclusions: Esophagography demonstrated lower sensitivity than CT, although its accuracy was higher, indicating that both methods can be used to evaluate patients with clinical signs of AL. C-reactive protein levels were not associated with AL.
Effects of Self-management Interventions on Diabetic Kidney Disease Progression and Related Health Behaviors in Type 2 Diabetes Mellitus: A Systematic Review
(Brieflands, 2026-09-30) Dongmei CHU; Bingyang Liu; Kim Lam Soh; Hasni Idayu Saidi; Salimah Japar; Dongmei CHU [0009-0000-6045-6067]; Bingyang Liu [0000-0002-1930-5141]; Kim Lam Soh [0000-0003-2404-828X]; Salimah Japar [0000-0001-9609-028X]
Context: Diabetic kidney disease (DKD), a common complication of diabetes, affects approximately 20%-40% of patients with diabetes and may progress to end-stage renal disease if not appropriately managed. Modifiable factors influencing DKD progression can be addressed through self-management. However, the effects of self-management interventions on clinical outcomes and self-care behaviors remain unclear. This systematic review evaluated the evidence on the impact of self-management interventions on DKD progression and related health behaviors among patients with type 2 diabetes mellitus (T2DM). Evidence Acquisition: This systematic review followed the PRISMA guidelines. Nine databases and one trial register were searched from inception to August 2025 for English- and Chinese-language studies of any design that evaluated self-management interventions targeting DKD progression. Three reviewers independently screened studies and assessed eligibility. Study quality was evaluated using the Cochrane risk-of-bias assessment tools, and data were extracted using a standardized form. Results: Twelve studies were included in the qualitative analysis. Nine studies reported improvements in glycemic control, and four reported improvements in renal function. Evidence regarding blood pressure, lipid profiles, and weight-related outcomes varied across studies. Eight studies reported improved self-management behaviors, and three reported improved self-efficacy. In addition, five studies suggested potential benefits for quality of life and mental health outcomes. Overall, the included studies suggested that self-management interventions may provide multidimensional benefits for patients with T2DM and DKD or those at high risk of DKD.
Twenty-Year Trends in HBsAg Seroprevalence and Associated Risk Factors Among Blood Donors in Sistan and Baluchestan, Iran (2005 - 2024)
(Brieflands, 2026-12-31) Abolhasan Safdari; Alireza Ansari Moghaddam; Soheila Khosravi; Mahdi Zarourati; Abolhasan Safdari [0000-0001-6793-1596]; Alireza Ansari Moghaddam [0000-0002-3267-7193]; Soheila Khosravi [0000-0002-1820-850X]; Mahdi Zarourati [0009-0008-9749-6466]
Background: Long-term surveillance of transfusion-transmitted infections is essential, particularly in border regions. Objectives: This study analyzed 20-year trends in hepatitis B virus (HBV) seroprevalence and associated risk factors among blood donors in Sistan and Baluchestan Province, Iran, from 2005 to 2024. Methods: This retrospective analysis included 935,864 blood donors. Screening methods evolved from manual enzyme-linked immunosorbent assay (ELISA; 2005 - 2009) to automated ELISA beginning in 2009, chemiluminescence immunoassay (CLIA) beginning in 2019, and nucleic acid testing (NAT) beginning in 2024. A nested case-control study of 300 HBsAg-positive and 300 HBsAg-negative donors was analyzed using multivariable logistic regression. Results: The overall HBsAg seroprevalence was 0.634% (5,930/935,864). Annual prevalence declined from 2.039% in 2005 to 0.189% in 2024 (relative reduction > 90%; P < 0.001), reaching a minimum of 0.019% in 2019. First-time donors had a higher prevalence than repeat donors (1.861% vs 0.021%; P < 0.001). Independent risk factors included household contact with an HBV-infected person (adjusted odds ratio [aOR] = 54.5), drug abuse (aOR = 19.4), a history of jaundice (aOR = 8.1), and knife wounds (aOR = 7.3). Higher education was a protective factor. Conclusions: HBsAg seroprevalence decreased by more than 90% over two decades, reflecting the success of national vaccination and donor-selection strategies. Expanding the repeat-donor pool and maintaining NAT are essential for further improving blood safety.