Brieflands

History

The company was first founded by Seyyed M. Miri and Seyed-M Alavian as an editorial group in a Medical Institute in 2007 to publish its medical journal. After three years of experience, the number of journals increased to 5 journals, and the company launched its first form of business as a VOF (collaboration) professional STM company in Heerlen, the Netherlands, which was called "Kowsarmedical Publishing." Respecting the publishing services (from submission to publishing), especially an in-house "Journal Management System," our journals increased to more than 60 STM journals between 2010 and 2019. Since 2022, "Brieflands" is the new brand name that acts as a "Science, Technical, Medical Publisher" that publishes more than 50 journals with the services provided by 97 expert employees in three different branches.

Business Profile

  • Brieflands is a Registered Trademark with record number 1454012.
  • Brieflands has been registered as a General partnership (Vennootschap onder firma) company in the Chamber of Commerce (Kamer van Koophandel) of the Netherlands since 2010.
  • Nedmedica is our related company which is specialized in Author Services. 
  • Our former branding name was Kowsarmedical Publishing (2010-2021).
 

Communities in Brieflands

Select a community to browse its collections.

Recent Submissions

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Panitumumab-Induced Severe Hypomagnesemia and Risk of Atrial Fibrillation and QT Prolongation: An Electrophysiologic Perspective
(Brieflands, 2026-12-31) Azin Alizadehasl; Haniyeh Faraji Azad; Sara Adimi; Amirhossein Shirinezhad; Azin Alizadehasl [0000-0002-8550-1378]; Sara Adimi [0000-0002-1060-6036]; Amirhossein Shirinezhad [0009-0003-7718-1938]
Introduction: Panitumumab-induced hypomagnesemia disrupts calcium and potassium channel function, prolongs the corrected QT (QTc) interval, and may create a substrate for atrial arrhythmogenesis. We describe a patient with metastatic colon cancer who developed severe hypomagnesemia and marked QTc prolongation during panitumumab therapy; however, atrial fibrillation did not occur. This case demonstrates rapid electrophysiological recovery after magnesium repletion and underscores the importance of cardiac monitoring in patients receiving epidermal growth factor receptor inhibitors. Case Presentation: A 68-year-old man with metastatic colon cancer receiving folinic acid, fluorouracil, and irinotecan plus panitumumab developed progressive hypomagnesemia, with the serum magnesium level decreasing from 0.78 mmol/L at baseline to 0.33 mmol/L by cycle 8, accompanied by hypokalemia. He remained asymptomatic. Before cycle 9, electrocardiography showed normal sinus rhythm without atrial fibrillation; however, the QTc interval had increased by 50 ms from baseline, from 410 to 460 ms. Panitumumab was withheld, and magnesium and potassium were repleted. Follow-up electrocardiography showed normalization of the QTc interval to 415 ms without atrial or ventricular arrhythmia. Conclusions: Panitumumab can cause clinically silent yet progressive hypomagnesemia, which may disrupt cardiac conduction and increase the risk of arrhythmias. Timely electrolyte repletion may reverse QTc prolongation, prevent arrhythmias, and allow continuation of anticancer therapy. Vigilant monitoring and prompt intervention are essential.
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State Responsibility for Ensuring the Right to Health in Mass Gatherings
(Brieflands, 2026-04-30) Mojtaba Dehghandar; Mirhamed Khani
Context: Mass gatherings (MGs), defined as concentrations of people assembled for a specific purpose, have major cultural, religious, and economic significance but also pose substantial public health risks, including communicable disease outbreaks, crush injuries, and environmental hazards. Evidence Acquisition: This review examines states’ responsibilities to protect health at MGs by analysing international human rights law, particularly Article 12 of the International Covenant on Economic, Social and Cultural Rights. It also considers obligations related to religious pilgrimages, international cooperation, accountability, climate change, and digital health governance. Results: States bear the primary and nondelegable responsibility for safeguarding the right to health of all MG participants. Fulfilling this obligation requires a comprehensive, multisectoral approach that includes proactive planning, robust risk assessment, adequate on-site health services, and effective surveillance and response systems. Conclusions: Failure to implement appropriate public health protections at MGs may constitute a breach of states’ legal duties to respect, protect, and fulfill the right to the highest attainable standard of health. Effective governance must also address emerging risks and ensure international cooperation and accountability.
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Association Between Serum 25-Hydroxyvitamin D Levels and HbA1c/Fasting Plasma Glucose in Type 2 Diabetes Mellitus: Cross-sectional Study, Dezful Diabetes Clinic, Iran
(Brieflands, 2026-07-31) Hamid Karimi; Sepideh Ordookhani; Ali Arianezhad; Mohammad Dorchin; Hamid Karimi [0000-0001-5527-4082]; Sepideh Ordookhani [0009-0008-9188-3457]; Ali Arianezhad [0009-0002-7706-9586]; Mohammad Dorchin [0009-0006-1360-6978]
Background: Vitamin D deficiency is common among individuals with type 2 diabetes mellitus (T2DM) and has been suggested to affect glucose metabolism. However, the evidence regarding its association with glycemic control remains inconsistent. Objectives: This study aimed to examine the association between serum 25-hydroxyvitamin D (25(OH)D) status and glycemic indices, including HbA1c and fasting plasma glucose, in patients with T2DM. Methods: This cross-sectional study included 180 adult patients with T2DM who attended the Dezful Diabetes Clinic between December 2023 and December 2024. Fasting plasma glucose (FPG), glycated hemoglobin (HbA1c), and serum 25-hydroxyvitamin D [25(OH)D] concentrations were measured using standardized laboratory methods. Vitamin D status was categorized as deficient (< 20 ng/mL), insufficient (20 - 30 ng/mL), or sufficient (> 30 ng/mL). Demographic characteristics were recorded, and glycemic indices were compared according to sex, age group, and vitamin D status. Pearson correlation and multivariable linear regression analyses adjusted for age, sex, Body Mass index (BMI), and antidiabetic medication use were performed. Results: The mean age of the participants was 55.02 ± 10.95 years, and 72.2% were female. The mean FPG and HbA1c values were 154.1 ± 60.7 mg/dL and 8.14 ± 2.10%, respectively. Overall, 35.0% of participants had vitamin D deficiency and 31.1% had insufficiency (combined prevalence, 66.1%). Serum 25(OH)D was significantly inversely correlated with HbA1c (r = -0.23; 95% CI, -0.36 to -0.09; P = 0.002) and FPG (r = -0.17; 95% CI, -0.31 to -0.02; P = 0.022). Mean HbA1c levels were significantly lower in males than in females (7.6 ± 1.7% vs. 8.3 ± 2.2%; P = 0.01) and differed significantly across age groups (P = 0.007). A higher proportion of patients with vitamin D deficiency were classified as diabetic according to HbA1c than were those with sufficient vitamin D levels (85.7% vs. 72.1%; χ2 = 6.11, df = 2, P = 0.047). Conclusions: Vitamin D deficiency was highly prevalent among patients with T2DM and was significantly inversely correlated with HbA1c and FPG, with a significant categorical association with HbA1c-defined glycemic control. Assessment of vitamin D status may be relevant to the clinical management of T2DM; however, longitudinal studies are needed to establish causality.
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Factors Associated with Upgrading of Pathological ISUP Grading Following Radical Prostatectomy: A Retrospective Cohort Study
(Brieflands, 2026-05-31) Reza Shahrokhi-Damavand; Emad Moaied Abedi; Samaneh Esmaeili; Ardalan Akhavan Tavakoli; Shahab Aali; Ehsan Kazemnezhad Leili; Samaneh Esmaeili [0000-0003-3826-758X]; Ardalan Akhavan Tavakoli [0000-0002-6385-4332]; Shahab Aali [0009-0004-1717-2690]; Ehsan Kazemnezhad Leili [0000-0002-9195-9094]
Background: Previous studies have reported discordance in Gleason scores (GSs) between needle biopsy results and radical prostatectomy (RP) specimens. Objectives: To identify factors associated with International Society for Urological Pathology (ISUP) grade upgrading in patients who underwent radical prostatectomy (RP). Methods: In this retrospective cohort study, 110 patients with prostate cancer who underwent RP between 2019 and 2024 were evaluated. Demographic data, laboratory results, pathological characteristics, and MRI findings (Prostate Imaging-Reporting and Data System [PI-RADS], intraprostatic cancerous lesions, extracapsular extension, and seminal vesicle invasion) were extracted from patient records. Patients were classified into two groups according to the presence or absence of ISUP grade upgrading. Upgrading was defined as any increase in ISUP grade in the RP specimen compared with that in the needle biopsy. Univariate and multivariate logistic regression analyses were performed to evaluate predictive factors for upgrading. Results: Among the 110 patients (mean age, 62.97 years), 47 (42.7%) had ISUP upgrading on RP compared with biopsy. In univariable analysis, age, PSA, PSA density (PSAD), the time interval between biopsy and RP, and MRI parameters were not significantly associated with ISUP upgrading (P > 0.05). In multivariate logistic regression analysis, both a free/total PSA (f/tPSA) ratio ≤ 10% (OR = 0.27, 95% CI, 0.11 - 0.65, P = 0.004) and an ISUP grade of 1 on biopsy (OR = 0.25, 95% CI, 0.11 - 0.57, P = 0.001) were independently associated with the risk of upgrading. Conclusions: An f/tPSA ratio of ≤ 10% and an ISUP grade of 1 on biopsy were associated with pathological upgrading. Prospective studies are required to validate these findings.
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A Dedicated Pediatric Intravenous Therapy Team: Five-Year Outcomes of a Nurse-Led Management Model
(Brieflands, 2026-07-28) Jin Ting; Xu Hong Zhen; Hongqin Zhou
Background: A dedicated pediatric intravenous therapy team may improve the quality, safety, and efficiency of vascular access care by centralizing specialized nursing expertise, standardizing technical procedures, and enhancing complication management. Objectives: This study aimed to describe the establishment and management of a dedicated pediatric intravenous therapy team at a single children's hospital and to report observed changes in service quality and efficiency over a 5-year period using a retrospective before-and-after observational design. Methods: The team was established in 2019. Management strategies included role definition, eligibility criteria, workflow standardization, and performance-based incentives. Indicators of service volume, puncture success rate, complication rate, and regional influence were compared descriptively between the preimplementation and postimplementation periods from 2019 to 2024. Results: After the team was established, the compound annual growth rate of outpatient maintenance procedures reached 44.5%, and the success rate of ultrasound-guided puncture exceeded 98%. The catheter-related infection rate declined to < 1‰. The mean satisfaction rate among pediatric patients and their parents was 99.3%. Although the total number of complications during in-hospital consultations decreased, exudation/bleeding at the PICC puncture site emerged as a new management priority, accounting for 35.3% of complications in 2024. Out-of-hospital consultations rebounded by 80.0% in 2024, and the team provided systematic training to 18 visiting nurses. Conclusions: In this single-center before-and-after observational study, the implementation of a dedicated pediatric intravenous therapy team was associated with improvements in observed nursing quality and efficiency. This model provides a practice-based reference for specialized pediatric nursing management; however, its causal effectiveness requires validation through more rigorous study designs.