Brieflands

History

The company was first founded by Seyyed M. Miri and Seyed-M Alavian as an editorial group in a Medical Institute in 2007 to publish its medical journal. After three years of experience, the number of journals increased to 5 journals, and the company launched its first form of business as a VOF (collaboration) professional STM company in Heerlen, the Netherlands, which was called "Kowsarmedical Publishing." Respecting the publishing services (from submission to publishing), especially an in-house "Journal Management System," our journals increased to more than 60 STM journals between 2010 and 2019. Since 2022, "Brieflands" is the new brand name that acts as a "Science, Technical, Medical Publisher" that publishes more than 50 journals with the services provided by 97 expert employees in three different branches.

Business Profile

Brieflands is a Registered Trademark with record number 1454012.
Brieflands has been registered as a General partnership (Vennootschap onder firma) company in the Chamber of Commerce (Kamer van Koophandel) of the Netherlands since 2010.
- KvK number: 89235444.
- BTW (VAT) number: NL864918896B01 (check online at VIES )
- RSIN: 864918896
Nedmedica is our related company which is specialized in Author Services.
Our former branding name was Kowsarmedical Publishing (2010-2021).

Communities in Brieflands

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Recent Submissions

Barriers and Facilitators to Implementing the WHO Integrated Care for Older People Approach in Low- and Middle-Income Countries: Bridging the Evidence-to-Implementation Gap
(Brieflands, 2026-11-30)
Reza Saeidi
;
Mohammad Kordkatouli
;
Reza Saeidi [0000-0002-9033-3321]
;
Mohammad Kordkatouli [0009-0006-3008-6820]
This article does not have an abstract.
Melatonin as a Multi-Target Therapeutic Strategy for Sepsis-Associated Acute Kidney Injury: Mechanistic Insights and Translational Perspectives
(Brieflands, 2026-03-31)
Mahnaz Sadat Hosseini
;
Homeira Masoudi
;
Yunes Panahi
;
Mohammadreza Hajiesmaeili
;
Mahnaz Sadat Hosseini [0000-0002-1268-9760]
Context: Sepsis-associated acute kidney injury (SA-AKI) is a frequent and life-threatening complication of sepsis that increases mortality, prolongs stays in the intensive care unit, and raises healthcare costs. Despite advances in supportive care, no pharmacological therapy has consistently prevented or reversed SA-AKI. Mitochondrial dysfunction, oxidative stress, excessive inflammation, and regulated cell death are central to its pathogenesis. Melatonin, an endogenous indoleamine with potent antioxidant and immunomodulatory properties, has emerged as a promising multi-target therapeutic candidate. This review summarizes current experimental and emerging clinical evidence on the renoprotective effects and molecular mechanisms of melatonin in SA-AKI. Evidence Acquisition: A structured narrative review was conducted using a predefined, nonsystematic literature search of PubMed/MEDLINE and Google Scholar from database inception through January 31, 2026. Original experimental and clinical studies evaluating melatonin or melatonergic agents in SA-AKI were included. Two reviewers independently screened the studies, with disagreements resolved by consensus. Findings were synthesized narratively because of substantial heterogeneity. Results: Ten eligible studies, predominantly involving rodent models of sepsis induced by lipopolysaccharide or cecal ligation and puncture, were included. Melatonin consistently improved renal function and histopathological outcomes while reducing oxidative stress and inflammation. Mechanistically, it preserved mitochondrial integrity by enhancing mitophagy through the PTEN-induced kinase 1 (PINK1)/Parkin and SIRT3–mitochondrial transcription factor A (TFAM) pathways and by suppressing cyclic GMP–AMP synthase–stimulator of interferon genes (cGAS–STING), nuclear factor kappa B (NF-κB), and NOD-like receptor protein 3 (NLRP3) inflammasome signaling. Additional protective effects included activation of the nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) pathway and inhibition of apoptosis and ferroptosis. Combination therapy with mesenchymal stem cells or ascorbic acid showed additive benefits in preclinical studies. Conclusions: Current evidence supports melatonin as a biologically plausible, multitarget therapeutic candidate for SA-AKI. However, robust clinical trials are needed to establish its optimal dose, timing, safety, and efficacy in patients.
Health System Responsiveness and Client Satisfaction Among Recipients of Humanitarian Services Provided by the Iranian Red Crescent Society in Razavi Khorasan Province, Iran: A Cross-Sectional Study
(Brieflands, 2026-10-31)
Maliheh Khalvati
;
Pirhossein Kolivand
;
Parisa Paran
;
Fariba Mahouti
;
Soraya Gharebaghi
Background: Health system responsiveness (HSR) captures how health systems address clients' nonmedical expectations, including dignity, autonomy, confidentiality, communication, and prompt attention. Despite its recognized importance in humanitarian settings, empirical evidence on HSR and its relationship to client satisfaction in these contexts remains limited. Objectives: This study assessed HSR and client satisfaction among recipients of humanitarian services provided by the Iranian Red Crescent Society in Razavi Khorasan Province, Iran. Methods: A descriptive-analytical cross-sectional survey was conducted in 2023 across 27 counties. A multistage sampling design with convenience sampling within service strata was used to enroll 1,384 recipients of social, pharmaceutical, medical, and rehabilitation services. Data were collected using the McMurtry Client Satisfaction Scale (25 items, four domains) and the World Health Organization (WHO) HSR Questionnaire (25 items, eight domains). Exploratory factor analysis and confirmatory factor analysis were used to evaluate construct validity. Group differences were assessed using t tests and analysis of variance (ANOVA). The relationship between HSR and satisfaction was examined using Pearson correlation and analysis of covariance. Results: A total of 1,384 recipients across 27 counties were surveyed. Both instruments demonstrated sound psychometric properties (satisfaction α = 0.737; responsiveness α = 0.872), supporting a four-factor satisfaction structure (52.5% variance) and an eight-factor responsiveness structure aligned with World Health Organization (WHO) domains (62.1% variance), with good CFA fit for both. Mean scores were 76.47 (SD = 9.32) for satisfaction and 82.54 (SD = 13.06) for responsiveness. Female participants and recipients of pharmaceutical services reported higher satisfaction; no significant differences emerged by age, education, or residence. HSR and satisfaction were not significantly correlated (r = 0.02, P = 0.454), and this null association persisted after adjustment for gender and service type. Conclusions: Satisfaction and responsiveness levels were both moderate to high, although responsiveness scores were consistently higher than satisfaction scores. Contrary to expectations, HSR and client satisfaction were not significantly correlated, suggesting that these constructs capture distinct aspects of the service experience in this humanitarian context. The findings highlight social services and rehabilitation as priority areas for quality-improvement efforts within Red Crescent humanitarian programs.
Comparison of the Effects of Abdominal Massage with and Without Peppermint Extract on Gastric Residual Volume and Abdominal Distension in Patients Receiving Enteral Feeding in the Intensive Care Unit: A Clinical Trial
(Brieflands, 2026-03-31)
Marzie Safari
;
Hossein Shahdadi
;
Mozhgan Rahnama
;
Abdolghani Abdollahimohammad
;
Mahdieh Poodineh Moghadam
Background: Enteral feeding intolerance is common among intensive care unit (ICU) patients and often manifests as elevated gastric residual volume (GRV) and abdominal distension. Nonpharmacological interventions may offer safe alternatives to drug therapy. Objectives: This study aimed to compare the effects of abdominal massage with and without peppermint extract on GRV and abdominal distension in patients in the intensive care unit (ICU) who were receiving enteral nutrition. Methods: A single-blind randomized clinical trial was conducted in which participants were blinded to group allocation. A total of 50 patients who met the inclusion criteria were randomly assigned by lottery using numbered, sealed envelopes to receive abdominal massage with peppermint extract (n = 25) or without peppermint extract (n = 25). The intervention lasted 3 consecutive days and consisted of 20-minute abdominal massage sessions twice daily. According to the intensive care unit (ICU) protocol, patients received gavage feeding every 3 hours, resulting in 2 feeding sessions during the 6-hour interval between massage sessions. Gastric residual volume was assessed twice daily: immediately before the first massage session and 1 hour after the second session. Abdominal circumference was also measured twice daily, before the first massage session and after the second session. Data were analyzed using IBM SPSS Statistics version 23. Results: The independent t-test revealed a statistically significant between-group difference in mean GRV before and after massage during the 3-day intervention period (P < 0.001). Analysis of covariance, adjusted for baseline values, also confirmed a significant between-group difference (P < 0.001). However, no statistically significant between-group difference was found in mean abdominal circumference (P ≥ 0.05). Conclusions: Abdominal massage with peppermint extract was more effective than massage alone in reducing GRV among enterally fed neurological intensive care unit (ICU) patients. Given the low cost and ease of use of peppermint extract, this intervention may be considered a useful adjunctive nursing measure to reduce GRV. Although no significant reduction in abdominal distension was observed, this finding does not necessarily indicate a lack of efficacy; rather, it suggests the need for a larger sample size with adequate power to detect this outcome.
Lived Experiences of Individuals After Orchiectomy: A Content Analysis
(Brieflands, 2026-12-31)
Hossein Shahdadi
;
Mozhgan Rahnama
;
Abdolghani Abdollahimohammad
;
Hajar Noori Sanchooli
;
Abdolbaset Rigimotlagh
Background: Understanding the experiences of individuals who have undergone orchiectomy is crucial for healthcare providers to support them during treatment and recovery. Objectives: This study used content analysis to explore the experiences of individuals who had undergone orchiectomy. Methods: This qualitative study used conventional content analysis. Purposive sampling was used to recruit 11 individuals who had undergone orchiectomy. Data were collected through semistructured interviews, and the analysis followed the method described by Graneheim and Lundman. Rigor, trustworthiness, and ethical considerations were addressed, including procedures for identifying and referring participants who disclosed severe distress during interviews. Results: Two main categories and eight subcategories were identified: experiencing crises (shock and event impact, physical challenges, sexual and reproductive system concerns, emotional and masculine identity loss, and social stigma) and coping and adaptation (perceived life limitations, behavioral adaptations, and support systems). Seven participants had undergone bilateral orchiectomy, and four had undergone unilateral orchiectomy. Clinical details, such as the indication for surgery, testosterone replacement, prosthesis use, and fertility counseling, were not systematically collected. Conclusions: Individuals who had undergone orchiectomy experienced shock and physical and functional changes in the sexual and reproductive system, particularly among those who had undergone bilateral surgery. These changes were interrelated with emotional and masculine identity loss, as well as social stigma. Single participants described marriage as unattainable. Spousal and social support were described as central to coping; therefore, further evaluation of spouse and family education programs may be beneficial. The well-being of individuals after orchiectomy should be enhanced by addressing their physical, psychological, and emotional needs.