Brieflands
History
The company was first founded by Seyyed M. Miri and Seyed-M Alavian as an editorial group in a Medical Institute in 2007 to publish its medical journal. After three years of experience, the number of journals increased to 5 journals, and the company launched its first form of business as a VOF (collaboration) professional STM company in Heerlen, the Netherlands, which was called "Kowsarmedical Publishing." Respecting the publishing services (from submission to publishing), especially an in-house "Journal Management System," our journals increased to more than 60 STM journals between 2010 and 2019. Since 2022, "Brieflands" is the new brand name that acts as a "Science, Technical, Medical Publisher" that publishes more than 50 journals with the services provided by 97 expert employees in three different branches.
Business Profile
- Brieflands is a Registered Trademark with record number 1454012.
- Brieflands has been registered as a General partnership (Vennootschap onder firma) company in the Chamber of Commerce (Kamer van Koophandel) of the Netherlands since 2010.
- KvK number: 89235444.
- BTW (VAT) number: NL864918896B01 (check online at VIES)
- RSIN: 864918896
- Nedmedica is our related company which is specialized in Author Services.
- Our former branding name was Kowsarmedical Publishing (2010-2021).
Communities in Brieflands
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Recent Submissions
Prevalence of Iron Deficiency in Non-anemic Pregnant Women During the First Trimester: A Prospective Cohort Study
(Brieflands, 2025-04-30) Nayereh Rahmati; Zahra Naeiji; Sepideh Ashrafivand; Manizheh Toryal
Background: The present study aimed to investigate the prevalence of iron deficiency in non-anemic mothers during the first trimester of pregnancy. Methods: A prospective cohort study was conducted involving 876 pregnant women who visited Mahdieh Hospital in 2022. Blood samples were collected to measure hemoglobin (Hb), hematocrit (HCT), and ferritin levels. A ferritin level below 30 ng/dL was considered indicative of iron deficiency. Results: The study found that patients with ferritin levels ≥ 30 ng/dL had higher average age (95% CI: -1.92 to -0.16; P = 0.02) and Hb levels (95% CI: -0.51 to -0.15; P < 0.001) were higher in patients with ferritin levels ≥ 30 ng/dL. No significant correlation was found between ferritin levels and weight (95% CI: -2.78 to 1.01; P = 0.36), height (95% CI: -0.45 to 1.11; P = 0.40), or BMI (95% CI: -0.86 to 1.27; P = 0.44). Additionally, there was no significant relationship between ferritin levels and parity (P = 0.06), education (P = 0.85), income (P = 0.98), dietary habits (P = 0.27), or abnormal uterine bleeding (AUB) (P = 0.51) with ferritin level in patients (P > 0.05). However, the incidence of abortion was higher in patients with ferritin levels ≥ 30 ng/dL (P = 0.01). Logistic regression analysis revealed that only Hb levels had a statistically significant relationship with ferritin levels (95% CI: 0.02 to 0.28; P = 0.02). Conclusions: In general, it can be said that Hb and abortion factors can be related to iron deficiency in pregnant women in the first trimester of pregnancy.
Effect of Transcutaneous Electrical Nerve Stimulation on Shoulder Pain: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
(Brieflands, 2025-03-31) Tannaz Ahadi; Nafiseh Akbari; Lobaneh Janbazi; Bijan Forogh; Sepanta Hatam; Effat Sadooghi-Moshaki; Masumeh Bagherzadeh Cham; Tannaz Ahadi [0000-0002-6963-2503]; Lobaneh Janbazi [0000-0002-1254-9709]; Bijan Forogh [0000-0002-3718-8719]; Masumeh Bagherzadeh Cham [0000-0002-2781-5387]
Context: Transcutaneous electrical nerve stimulation (TENS) is a standard conservative treatment for shoulder pain. Objectives: This systematic review aims to explore the effectiveness of TENS in relieving shoulder pain. Methods: A comprehensive search was performed on PubMed, EMBASE, Scopus, Web of Knowledge, and Cochrane databases from inception until May 2023. The primary outcomes were pain and range of motion. The risk of bias (ROB) was evaluated using the Cochrane ROB tool by two authors. The GRADE approach was used to evaluate the level of certainty in the evidence. Results: The meta-analysis comprised 16 studies, including 1,024 participants with shoulder pain. The TENS was as effective as the control group in pain reduction immediately (I2: 91%; P = 0.7) and at long-term follow-up (I2: 50%; P = 0.11). The certainty of the evidence was very low. The TENS is equally effective as the control group in improving shoulder range of motion at different times. Conclusions: The TENS has the same effectiveness as the control group in reducing pain and improving range of motion. High-quality randomized controlled trials (RCTs) with larger sample sizes and longer follow-ups should be conducted to investigate the effectiveness of TENS on pain and range of motion in individuals with shoulder pain of different etiologies.
Perceived Stress Among Nurses in Public Hospitals of the Northern Region of Morocco and Its Correlation with Their Social Anxiety: A Cross-Sectional Study
(Brieflands, 2025-06-30) Aya Rahoui Chairi; Maria Leyre Lavilla Lerma; Nabil Benomar; Nabila Rouahi; Aya Rahoui Chairi [0009-0009-7022-8477]; Maria Leyre Lavilla Lerma [0000-0002-1295-1968]; Nabil Benomar [0000-0002-7297-6171]; Nabila Rouahi [0000-0001-8128-2350]
Background: Professional stress in healthcare workers, particularly among nurses, is a pressing issue globally, affecting their well-being and job performance. Objectives: This study aimed to assess the level of perceived stress among nurses in the northern region of Morocco, identify related socio-demographic and professional factors, and analyze the correlation between perceived stress and social anxiety scores. Methods: A cross-sectional study was conducted among 494 nurses in the northern region of Morocco in 2022. The sample size was estimated using Bernoulli sampling method. Participants were selected through stratified random sampling to ensure proportional representation across hospitals. Data were collected using a self-administered questionnaire based on Perceived Stress Scale (14 items version) (PSS14), the Liebowitz Social Anxiety Scale (LSAS) and a section covering socio-demographic and professional characteristics. Statistical analyses, including descriptive statistics, inferential tests, and regression analysis, were done using SPSS v.22 (IBM Corp, Armonk, NY, United States of America). Results: The study findings showed that 87% of nurses experienced moderate levels of perceived stress, with a mean score of 28.14 ± 6.02. In terms of social anxiety, a mean score of 53.17 ± 21.10 was noted. Risk factors associated with stress levels included gender (t = -2.951; P = 0.003), age (F = 3.466; P = 0.032) and nursing specialty (F = 2.909; P = 0.021). A moderate positive correlation was observed between perceived stress and social anxiety (r = 0.350, P = 0.001) with 12.2% of the variance in social anxiety can be explained by perceived stress (R2 = 0.122). Conclusions: The study stated that the majority of nurses had a moderate perceived stress and social anxiety in northern Morocco, with significant variations based on gender, age, and nursing specialty. A significant correlation was found between perceived stress and social anxiety. These findings underscore the need for targeted interventions to reduce stress and improve labor conditions for nurses.
The Effect of Wrist Circumference on Vascular Stiffening Due to Body Mass Index, Weight, Body Surface Area, and Waist Circumference as Mediators
(Shiraz University of Medical Sciences, 2025-12-31) Noor Mohammad Noori; Maryam Nakhaee Moghadam; Alireza Teimouri; Noor Mohammad Noori [0000-0002-0732-6412]; Maryam Nakhaee Moghadam [0000-0002-0080-862X]; Alireza Teimouri [0000-0002-8356-4260]
Background: Wrist circumference is emerging as a potential indicator of vascular health, but its relationship with vascular stiffening remains under explored. Objectives: This study investigates the mediating roles of Body Mass Index (BMI), weight, body surface area (BSA), and waist circumference (WC) in the association between Wrist circomfrence and vascular stiffness. Methods: This cross-sectional study was conducted to examine the mediating effects of BMI, weight, BSA, and WC on the association between wrist circumference and vascular stiffness in children and adolescents aged 5 - 18 years who referred to the pediatric clinics affiliated with Zahedan University of Medical Sciences (ZaUMS) in the years 2022 and 2023. Physical examinations and standardized measurements of wrist circumference, BMI, weight, BSA, and WC were conducted, with vascular stiffness parameters including arterial distensibility, Aortic Stiffness Beta Index, and pressure strain elastic modulus evaluated. Results: The analysis revealed that BMI, weight, BSA, and WC significantly mediated the relationship between wrist circumference and specific vascular stiffness measures, notably for Aortic Stiffness Beta Index and pressure strain elastic modulus. Sobel test results indicated significant mediation effects for BMI, BSA, and WC in both right and left wrist circumferences, though mediation was not significant for arterial strain. Conclusions: The findings underscore the importance of body composition variables in cardiovascular health assessments, suggesting that indirect effects (IDE) of wrist circumference on vascular stiffness can vary by the type of body composition metric and vascular parameter. These insights offer potential pathways for identifying at-risk populations and tailoring cardiovascular interventions based on anthropometric assessments.
Design, Synthesis, and Evaluation of Cytotoxic Effects of Functional Fatty Acid Derivatives as Potential Antineoplastic Agents for Breast Cancer
(Brieflands, 2025-12-31) Maryam Hosseini; Farzad Kobarfard; Salimeh Amidi; Shaya Mokhtari; Anna Sedaghat; Soraya Shahhosseini; Maryam Hosseini [0009-0001-1868-9876]; Farzad Kobarfard [0000-0001-6679-3275]; Salimeh Amidi [0000-0002-6032-3237]
Background: Breast cancer is among the most prevalent cancers in women and is the leading cause of mortality among women worldwide. Although a definitive cure for breast cancer remains elusive, essential fatty acids offer a promising therapeutic avenue. Objectives: The present study aimed to synthesize 16 derivatives of docosahexaenoic acid (DHA) and linoleic acid (LA) and evaluate their anti-cancer properties in vitro. Methods: Fourteen derivatives of LA and DHA were synthesized using a coupling method, while two ethylenediamine derivatives were synthesized via an ester intermediate. Molecular modeling was conducted using AutoDock Vina software. The cytotoxic effects of all compounds were assessed using the MTT assay on breast adenocarcinoma (MCF-7) cells. The mechanism of cell death induction by derivatives with the most favorable EC50 values was determined through annexin V-FITC/PI flow cytometry analysis, focusing on early and late apoptosis. Results: Docking results revealed that these compounds effectively interact with residues in the PTPB1 active site. All synthesized DHA and LA derivatives demonstrated cytotoxic effects on the MCF-7 cell line, with no significant cytotoxicity observed in normal human dermal fibroblasts (HDFs). Compounds D3 and L3, with EC50 values of 15.96 ± 2.89 μM and 24.64 ± 1.81 μM, respectively, were identified as the most potent anti-cancer compounds among the derivatives. Conclusions: The findings indicate that these functional fatty acid derivatives significantly reduce cancer cell viability. In addition to necrosis, compounds L3 and D3 induced apoptosis, with apoptosis rates of 20.5% and 47.1%, respectively.