Primary Splenic Lymphoma, a Rare yet Possible Diagnosis: A Case Report and Review of the Literature

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AuthorParima Safeen
AuthorMohammad Ali Moradi Ghadien
AuthorAthena Alipour Fazen
AuthorHassan Peyvandien
OrcidParima Safe [0000-0002-3398-9084]en
OrcidHassan Peyvandi [0000-0003-2891-0877]en
Issued Date2019-09-07en
AbstractIntroduction: The spleen is subject to a variety of benign and malignant disorders, which can be manifested by nonspecific symptoms or signs. Hence, the diagnosis is often made based on radiological examinations and histopathological studies. Case Presentation: Herein we present a case report of a patient with pathologically approved primary splenic lymphoma (PSL). The patient was a 63-year-old woman presented with abdominal pain, predominantly in the left upper quadrant, since 1 month. Complete blood count (CBC) was normal except for mild anemia. Liver enzyme studies showed an elevated alkaline phosphatase level. Ultrasound (US) depicted a huge hypoechoic splenic mass and computed tomography (CT) confirmed the lesion to be a hypodense mass partially exophytic from the superior aspect of the spleen measuring up to 124 mm in size. The patient underwent a midline laparotomy and splenectomy and the spleen was sent for histopathological examination, which revealed high-grade B-cell lymphoma measuring 17 × 16 × 10 cm in size with capsular invasion and without any lymphovascular invasion. Conclusions: This case report highlights the importance of considering splenic lymphoma as a differential diagnosis, although rare, in a patient with abdominal pain and nonspecific clinical findings.en
DOIhttps://doi.org/10.5812/ijcm.96494en
KeywordAbdominal Painen
KeywordCase Reporten
KeywordHigh-Grade B-Cell Lymphomaen
KeywordSpleenen
KeywordSplenectomyen
PublisherBrieflandsen
TitlePrimary Splenic Lymphoma, a Rare yet Possible Diagnosis: A Case Report and Review of the Literatureen
TypeCase Reporten

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