Relationship Between Serum Ferritin, TIBC Level and <i>Helicobacter pylori</i> Infection

Abstract

Background: In iron deficiency anemia (IDA), serum ferritin level is decreased and total iron binding capacity (TIBC) is increased Objectives: In this study the relationship between H. pylori infection and iron deficiency anemia were studied. Methods: This research was a cross-sectional study. TIBC and ferritin levels were measured in 133 patients, suspected to H. pylori infection, then serum levels of IgM and IgG antibody against H. pylori infection were measured Results: From 133 patients, 97 were females (72.93%) and 36 males (28.07%), 36 of them (23 women and 13 men) have a TIBC levels more than 400 ug/dL and ferritin levels were less than 12ng/dL. Twenty patients had IgG antibodies and 5 patients had IgM against H. pylori. Conclusions: The results show the association between H. pylori infection and increased levels of TIBC and decreased serum ferritin.