Regenerative Medicine And Perioperative Hypoxic Organ Damage: Targeting Hypoxia-Inducible Factors
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Date
2022-03-31
0000-0003-3430-5075 Journal Title
Journal ISSN
Volume Title
Publisher
Brieflands
Abstract
Regenerative medicine is defined by utilizing body’s own repair mechanisms in order to restore normal function of tissues. An important perioperative cause of organ injury is hypoperfusion mostly due to hypoxia. Hypoxia can promote genomic pathway and increase the level of hypoxia-inducible factors (HIF). In this review we introduce HIF as a pioneer role of regenerative medicine for prevention of perioperative complications.