Increase Expression of HBsAg in Transgenic Potato Plants and Challenges of Vaccine Production in Transgenic Plants

Abstract

The hepatitis B virus is a dangerous infectious agent, with an estimated 300 million carriers worldwide. Therefore, developing effective vaccine production methods is essential. One such method involves the use of transgenic plants. Several factors influence foreign gene expression in transgenic plants, including the type of genes, their chromosomal location, and the promoter used. Based on these factors, various expression cassettes can be designed for transgenic plants.