Antibody response to Streptokinase
| Author | A Afshari | en |
| Author | E Holme | en |
| Author | S Hillis | en |
| Issued Date | 2000-12-31 | en |
| Abstract | Abstract Background: Streptokinase is administered during acute myocardial infarction (AMI). It is prepared from beta haemolytic streptococci and in some cases pre-existing antibodies may compromise the use of streptokinase. Objective: To study levels of anti-streptokinase antibodies in AMI patients during thrombolytic therapy. Methods: Specific IgG, IgA, IgM and anti-streptokinase antibodies (ELISA) were studied in 246 cases. Pre and post-therapy levels of these antibodies were examined in 10 cases given streptokinase for AMI. Findings: Neutralizing anti-streptokinase were detectable in 61.7% of the controls which 0.43% of them had levels above the normal range. Neutralizing anti-streptokinase antibodies showed a positive correlation with the level of IgG anti-streptokinase antibodies (r=+0.55, P | en |
| DOI | https://doi.org/ | en |
| Keyword | Keywords: Streptokinase | en |
| Keyword | Acute myocardial infarction (AMI) | en |
| Publisher | Brieflands | en |
| Title | Antibody response to Streptokinase | en |
| Type | Research Article | en |
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