Value of High-Sensitivity C-Reactive Protein, Chronotropic Index, and Heart Rate Recovery in Predicting Cardiac Iron Overload in Patients with Beta-Thalassemia Major

Abstract

Background: Iron-induced cardiomyopathy is the main cause of heart failure in patients with beta-thalassemia major (β-TM). Early diagnosis and timely cardiac iron overload (IO) therapy can improve patients’ prognosis.