International Cardiovascular Research Journal

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    The Effect of Elective Percutaneous Coronary Intervention of the Right Coronary Artery on Right Ventricular Function
    (Shiraz University of Medical Sciences, 2014-12-31) Farahnaz Nikdoust; Seyed Abdolhosein Tabatabaei; Akbar Shafiee; Atoosa Mostafavi; Maryam Mohamadi; Sareh Mohammadi
    Background: Right Ventricular (RV) dysfunction has been introduced as a predictor of mortality in acute myocardial infarction.
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    Advantages and Challenges of Telecardiology and Providing Solutions for Its Successful Implementation: A Scoping Review
    (Shiraz University of Medical Sciences, 2022-03-31) Nasim Aslani; Ali Garavand; Saeed Jelvay; Masoumeh Maleki; Mina Lazem; Sadegh Sharafi
    Context: Implementation of health information technologies such as telecardiology has always been associated with many challenges. Identifying these challenges and planning to address them can lead to success in their implementation. The present study aimed to identify the advantages and disadvantages of using telecardiology and to provide solutions for its successful implementation based on the obtained results. 
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    QT Dispersion after Thrombolytic Therapy
    (Shiraz University of Medical Sciences, 2014-12-31) Saeed Oni Heris; Behzad Rahimi; Gholamreza Farid aalaee; Mojgan Hajahmadi; Hojjat Sayyadi; Bahman Naghipour
    Background: QT dispersion (QTd) is equal to longer QTc minus shorter QTc measured by 12-lead electrocardiogram (ECG). QTd reflects inhomogeneity in repolarization of ventricular myocardium and because of easy and fast measurement of QTd, it can be used to predict high-risk patients for dysrhythmia after Acute Myocardial Infarction (AMI).
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    Cardiac Hydatid Cyst: An Unusual Cause of Chest Pain
    (Shiraz University of Medical Sciences, 2013-12-31) Esref Tuncer; Ugur Turk; Emin Alioglu
     
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    The Impact of Diabetes on Early and Midterm Outcome of Patients Undergoing Coronary Artery Bypass Grafting Surgery
    (Shiraz University of Medical Sciences, 2010-06-30) B Sohrabi; AR Yaghoubi; Samad Ghaffari
    Background: Diabetic patients constitute about 25% of patients undergoing coronary artery bypass graft surgery (CABG). The impact of diabetes on the results of this operation, especially in Asian patients is not well understood. The present study aims to evaluate the effect of this important risk factor on the early and midterm outcome following CABG. Methods: This study was performed in Shahid Madani Heart Hospital, Tabriz, Iran from April 1998 to April 2003. Considering our inclusion and exclusion criteria, 1269 patients available for follow up were enrolled and evaluated for their early (30 days) and midterm mortality. Results: Diabetic patients constituted 332 (26.2%) of our patients. Female gender, hypertension, hyperlipidemia and peripheral arterial disease (PAD) were more prevalent in diabetics. Early mortality was not significantly different between two groups (6.6% in diabetics vs. 5% in non-diabetics, P=0.300) and this was true for early cardiac death (6.3% in diabetics vs. 4.7% in nondiabetics, P=0.200). However, in midterm follow up of 4.1 ± 1.6 years, diabetic patients had significantly higher mortality (18.7% in diabetics vs. 11.2% in nondiabetics, P
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    A Study of Salt (Sodium Chloride) Content in Different Bread Consumed in Shiraz City in Spring/Summer 2009
    (Shiraz University of Medical Sciences, 2010-03-31) Mohammad Javad Zibaeenezhad; M Hooshangi; Firoozeh Abtahi; Seyed Taghi Heydari
    Background: Randomized controlled studies over the last 4 decades demonstrated that controlling blood pressure could reduce the risks of cardiovascular disease. The relationship between diet ingredient (particularly the salt) and blood pressure has been well established and since bread is the main element in population diet, especially in our country, the determination of sodium content of bread is of high priority and warrants further investigation. Method: A total of 204 bakeries were selected for this study and the amount of salt in different bread was measured once during spring and summer, using the method of Iran’s Organization for Standards and Industrial Investigation. The study was performed on 6 different kinds of bread baked in different districts of Shiraz city. Results: This study demonstrated that 17.9% of bread’s salt level in Shiraz exceeds the standard level and the remaining 82.1% is within the standard range. Mean percentage of bread’s salt was reported as 1.31 gram% . Conclusion: Compared to the previous reports, the results of present study fortunately showed a reduction of salt in bread during the last two decades. However, 17.9% of bread’s salt is yet more than the standard level.
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    Investigating the effects of hypertension on happiness scale and consequent quality of life in a middle-age population from Shiraz city
    (Shiraz University of Medical Sciences, 2018-12-31) Samiyeh Fouladivanda; Mohammad Javad Zibaeenezhad; Ebrahim Moghimi; Iman Razeghian-Jahromi
    Background
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    Reference Values of Fetal Mechanical PR Interval and Heart Rate-Corrected Fetal Mechanical PR Interval: Influence of Fetal Sex, Heart Rate, Gestational Age, and Maternal Age
    (Shiraz University of Medical Sciences, 2018-06-30) Ehsan Aghaei Moghadam; Elaheh Malakan Rad; Maryam Nikoufar; Azin Ghamari; Amin Doosti Irani; Armen Kocharian; Aliakbar Zeinaloo
    Background
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    Hydatid Cyst of Right Atrium: A Case Report
    (Shiraz University of Medical Sciences, 2015-06-30) Maral Mokhtari; Hooriah Momen Zadeh
    Cardiac hydatid cyst is rare and usually occurs in the setting of disseminated disease. Herein, we reported a case of isolated right atrial hydatid cyst misdiagnosed clinically as a tumor. A 65-year-old woman diagnosed as having large right atrial mass suspected of malignancy underwent resection of the cardiac mass. Histopathological examination showed laminated membrane and protoscolices of Echinococcus Granulosus. However, all other work-ups failed to document systemic diseases. Therefore, isolated cardiac hydatid cyst was diagnosed. Hydatid cysts should be considered in differential diagnosis of any cardiac mass, especially in endemic areas.
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    Circulating Endothelial-Derived Apoptotic Microparticles in the Patients with Ischemic Symptomatic Chronic Heart Failure: Relevance of Pro-Inflammatory Activation and Outcomes
    (Shiraz University of Medical Sciences, 2014-09-30) Alexander Berezin; Alexander A. Kremzer; Tatayna A. Samura; Yulia V. Martovitskaya
    Background: Endothelial-derived apoptotic microparticles (EMPs) play a pivotal role in endothelial dysfunction in hronic Heart Failure (CHF).
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    The Prevalence of Metabolic Syndrome and Its Components among Adults in a Rural Community, Fars, Iran
    (Shiraz University of Medical Sciences, 2015-06-30) Fariba Karimi; Dariush Jahandideh; Mohammadhossein Dabbaghmanesh; Mohammadreza Fattahi; Gholamhosein Omrani
    Background: Metabolic Syndrome (MetS) is prevalent in Asian countries, but there is limited information about its distribution in rural communities.
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    Long Term Follow up of Cardiac Calcified Amorphous Tumor in Major Thalassemia; A case series report
    (Shiraz University of Medical Sciences, 2021-09-30) Mojgan Parsaie; Mohaddeseh Behjati
    Introduction: Cardiac Calcified Amorphous Tumors (CATs) are rare non-neoplastic heart intracavitary mass lesions. Cardiac CATs may arise in any heart chamber and are characterized histopathologically by diffuse calcium infiltration. The recommended treatment of choice is complete resection of the mass through surgery. Herein, three cases with thalassemia were presented with significant CATs that remained asymptomatic during close observation without any surgical interventions.Case Presentation: The three patients suffered from thalassemia. One of them had a calcified mass (3.8 × 0.74 cm) in the right ventricle in the vicinity of ventricular trabeculations, which prolapsed into the tricuspid valve orifice that resulted in moderate to severe tricuspid regurgitation without the development of any stenosis. Another case had an irregular calcified mass (2.3 × 0.75 cm) in the roof of the left atrium. The third case had a large calcified mass with a mobile component in right ventricular trabeculation. Surgical resection of the mass was recommended in all the cases, but they were closely monitored without surgical intervention. During the five-year follow-up, they remained totally asymptomatic and had no cardiovascular or cerebral events.Conclusions: Immobile CATs in patients with thalassemia can be asymptomatic. Hence, they can be closely monitored and surgical intervention can be delayed for many years. 
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    The Prognosis of Primary Percutaneous Coronary Intervention after One Year Clinical Follow Up
    (Shiraz University of Medical Sciences, 2013-03-31) Yahya Dadjoo; Yadallah Mahmoody
    Objectives: The aim of this study was to evaluate the clinical outcomes, one year after primary percutaneous coronary intervention(PCI).
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    Presentation of Anomalous Origin of the Left Coronary Artery From the Pulmonary Artery with Left Sided Coronary Ostium in an Adult Patient
    (Shiraz University of Medical Sciences, 2009-06-30) Zahra Ojaghi Haghighi; H Poorzand; HA Bassiri
    An anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital coronary anomaly. It usually presents in infancy with intractable left sided heart failure. Most patients die in infancy, but survival into adulthood is possible. Patients may complain of dyspnea, syncope or effort angina. They may remain asymptomatic; or experience sudden death after exercise. A 56-year-old woman presented with a twomonth history of exertional chest discomfort. Echocardiography showed a coronary anomaly with preserved systolic function and no resting regional wall motion abnormality. The coronary and CT (computed tomography) angiography studies revealed the anomalous origin of the left coronary artery. A review of ALCAPA studies is presented along with images from the echocardiogram, coronary angiogram and CT scan performed for this case.
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    Current Clinical and Research Developments in Cardiovascular Multi-Detector Computed Tomography
    (Shiraz University of Medical Sciences, 2007-12-31) Paul Schoenhagen
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    Atrial Standstill as a Probable Cause of Stroke in A Young Female Patient; A Case Report
    (Shiraz University of Medical Sciences, 2020-12-31) Seyed Hamed Banihashem Rad; Ali Reza Heidari-Bakavoli
    Introduction:Atrial standstill is a rare cardiac arrhythmia, which may present with different clinical symptoms, including longstanding dyspnea, congestive heart failure, syncope, cerebrovascular accidents, and even sudden cardiac death. According to such various presentations, diagnosis of atrial standstill may be complicated despite a high level of suspicion.Case Presentation:The present report demonstrated a case of bilateral idiopathic atrial standstill in a young female patient. The initial presentation of the disorder was the prolonged history of dyspnea and reduced effort tolerance, which was complicated by an episode of ischemic stroke two years ago. The patient was discharged with oral anticoagulants and anti-convulsants, but she had discontinued medication arbitrarily and was diagnosed in an electrophysiological study prior to pacemaker placement because of the junctional rhythm and premature ventricular beats. She was finally diagnosed as a case of biatrial standstill, which was characterized by the absence of electrical and mechanical activity in both atrias. Single-chamber permanent pacemaker was successfully implanted and she was discharged with oral anticoagulants and was recommended for further evaluation for idiopathic or familial cardiomyopathy.Conclusions:Atrial standstill could present in a silent manner as longstanding dyspnea and reduced effort tolerance, and remain misdiagnosed even after the development of cerebral ischemia in the absence of a high level of suspicion. These patients are eligible to receive oral anticoagulants life-long, and implanting PPM is almost indicated. 
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    Atrial Fibrillation as a Risk Marker in Patients with Decompensated Heart Failure
    (Shiraz University of Medical Sciences, 2020-06-30) Maryam Nabati; Soheil Bakhshinasab; Ali asghar Farsavian; Fatemeh Rasolpor; Jamshid Yazdani- Charati
    Background
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    Should We Retain Half-Dose ARNIs in HFrEF? Lessons Learned from Reverse Remodeling using CORE-HF Real-World Data
    (Shiraz University of Medical Sciences, 2022-09-30) Irnizarifka Irnizarifka; Irsyad Ristiansah; Habibie Arifianto; Trisulo Wasyanto
    Background: Heart failure (HF) is a progressive health problem with high mortality and morbidity rates in both developed and developing countries. Patients with HF who develop reverse remodeling during treatment have better outcomes and lower mortality. Real-world data on the reverse remodeling effects of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor-neprilysin inhibitors (ARNIs) in Indonesians are yet to be available.
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    The Effects of Heart-Lung Bypass on Endothelial Function of Patients with Open Heart Surgery
    (Shiraz University of Medical Sciences, 2015-06-30) Mohammad Borzoee; Ali Reza Nezami; Gholamhossein Ajami; Hamid Amoozgar; Ahmad Amirghofran
    Background: Endothelium is an essential organ for maintaining an adequate vascular tone and preventing the pathological process of atherosclerosis. Heart-lung machine is a mechanical support for maintenance of blood circulation during open heart surgery. It has been shown that flow of blood through this circuit can induce complement activation, endotoxines production, and release of many inflammatory mediators.
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    Left Ventricular Mechanics in Isolated Rheumatic Mitral Stenosis ;Impact of loading condition on different parameters of left ventricular function
    (Shiraz University of Medical Sciences, 2021-06-30) Atoosa Mostafavi; Azin Alizadehasl; Shahin Shirani
    Background: Rheumatic mitral stenosis leads to depressed ventricular function, which is not detectable through the measurement of ejection fraction. Whether pancarditis or changes in loading condition results in subclinical Left Ventricular (LV) dysfunction has yet to be fully elucidated.Objectives: The aim of this study is to evaluate the effect of loading condition on left ventricular function.Methods: The present observational, case-control study was conducted on 104 cases who were referred to the echocardiography department including 71 patients with different severity degrees of rheumatic mitral stenosis and 33 healthy individuals with no past history of cardiac or other medical illnesses and with normal echocardiography who were matched with the cases in terms of age, gender, and body surface area. The strain, strain rate, rotation, torsion, and twist parameters of the left ventricle were measured via 2D speckle-tracking echocardiography. The data were analyzed using Kolmogorov–Smirnov test, independent student t-test, and one-way Analysis of Variance (ANOVA), as appropriated. Correlation analysis was also performed using linear regression, and the results were expressed as Pearson’s correlation coefficients.Results: The LV Global Longitudinal Strain (GLS), Global Longitudinal Strain Rate (GLsr), and Global Circumferential Strain Rate (GCsr), but not Global Circumferential Strain (GCS), basal and apical rotations, twist, and torsion, were significantly lower in the subgroup with progressive mitral stenosis (17.7%, 1.07s-1, 22.85%, and 1.05s-1, respectively) compared to the healthy group (19.76%, 1.17 s-1, 24.15%, and 1.27 s-1, respectively) (P = 0.001, 0.032, 0.104, and < 0.001, respectively). Increase in the severity degree of mitral stenosis was accompanied by a significant decrease in the mentioned parameters.Conclusions: The rheumatic process led to a reduction in ventricular function, which was detectable through the measurement of the GLS, GLsr, and GCsr, but not GCS, twist, rotation, and torsional parameters of the left ventricle. As the severity of the stenosis progressed, other indices of the LV function such as rotation, twist, and torsion decreased significantly, indicating their more susceptibility to loading conditions compared to the rheumatic process per se.