Salvia Officinalis and Cisplatin Effects on Pentylenetetrazole Induced Seizure Threshold

AuthorMir Hadi Khayate-Nourien
AuthorAli Namvaran-Abbasabaden
AuthorFarzaneh Tavakkolien
Issued Date2013-11-30en
AbstractBackground: Studies have shown that cisplatin have neuropathic effects and Salvia officinalis (SO) could have therapeutic effects on nervous system. The aim of this study was to investigate the effects of SO hydroalcoholic extract and cisplatin on pentylenetetrazole (PTZ) induced seizure in mice. Materials and methods: This is an experimental interventional study. For this purpose first group received normal saline, second group received SO extract, third group received cisplatin, in the fourth group received SO extract plus cisplatin and the subsequent seizure threshold was determined for each group. Results: The results showed that SO extract significantly (pen
DOIhttps://doi.org/en
KeywordSalvia officinalisen
KeywordCisplatinen
KeywordPentylenetetrazoleen
KeywordSeizureen
KeywordMiceen
PublisherBrieflandsen
TitleSalvia Officinalis and Cisplatin Effects on Pentylenetetrazole Induced Seizure Thresholden
TypeResearch Articleen

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