The Role of Wharton’s Jelly Mesenchymal Stem Cells in Skin Reconstruction
| Author | Ayoob Rostamzadeh | en |
| Author | Maryam Anjomshoa | en |
| Author | Soleiman Kurd | en |
| Author | Jia-Ke Chai | en |
| Author | Faeze Jahangiri | en |
| Author | Mohammad Ali Nilforoushzadeh | en |
| Author | Sona Zare | en |
| Orcid | Sona Zare [0000-0002-3109-6717] | en |
| Issued Date | 2015-06-30 | en |
| Abstract | Context: Stem cell therapy, especially in the segment of mesenchymal stem cells (MSCs), is one of the most promising areas of regenerative medicine. Evidence Acquisition: According to research conducted by various researchers, Wharton’s Jelly mesenchymal stem cells (WJMSCs) have several advantages compared to others sources, in regenerative medicine: WJMSCs are more primary cells; WJMSCs can be easily isolated and without invasive procedures; WJMSCs have no ethical problems; WJMSCs are more cost effective than other sources of MSCs. Also, WJMSCs were demonstrated to express stem cell mesenchymal markers. Results: Similar to bone marrow MSCs, WJMSCs express major histocompatibility complex (MHC) class I molecules. Conclusions: Although the aforementioned challenges must still be addressed, the potential of WJMSCs in skin regenerative clinical treatments is promising. | en |
| DOI | https://doi.org/10.17795/jssc30347 | en |
| Keyword | Wharton’s Jelly | en |
| Keyword | Mesenchymal Stem Cells | en |
| Keyword | Skin | en |
| Keyword | Cell- and Tissue-Based Therapy | en |
| Publisher | Brieflands | en |
| Title | The Role of Wharton’s Jelly Mesenchymal Stem Cells in Skin Reconstruction | en |
| Type | Review Article | en |