Analgesic Efficacy of Diclofenac and Paracetamol vs. Meperidine in Cesarean Section
| Author | Heidar Darvish | en |
| Author | Behrouz Memar Ardestani | en |
| Author | Sara Mohammadkhani Shali | en |
| Author | Ali Tajik | en |
| Issued Date | 2014-02-01 | en |
| Abstract | Background: One of the most important complications in cesarean surgery is postoperative pain, and different ways have been proposed to control it. Objectives: The purpose of this study was to determine the efficacy of Diclofenac and Paracetamol combination in comparison with Meperidine on postoperative pain after cesarean surgery. Patients and Methods: One hundred and twenty women candidates for elective cesarean section under spinal anesthesia categorized as ASA class I were selected and randomly assigned to receive either Diclofenac suppository at the end of the operation and thereafter 1 gram infused bolus of Paracetamol (group A), or 20 mg bolus of Meperidine after transition to recovery room (group B) to control postoperative pain. Results: Postoperative pain was present in recovery in 38.3% and 23.3% in groups B and A, respectively (P = 0.009). Postoperative pain was seen after six hours of operation in 38.7% and 16.7% in groups B and A, respectively (P = 0.010). Postoperative pain was present after 12 hours of operation in 38.3% and 15% in groups B and A, respectively (P = 0.002). The additive Meperidine use was the same between the two groups in recovery (P > 0.05). The additive Meperidine use was seen after six hours of operation in 26.7% and 6.7% in groups B and A, respectively (P = 0.013). The additive Meperidine use was seen after 12 hours of operation in 16.7% and none of the patients in groups B and A, respectively (P = 0.004). The frequency of drug adverse effects was the same between the two groups (P > 0.05). Conclusions: Totally, according to the obtained results it may be concluded that Paracetamol and Diclofenac combination would have a better efficacy in postoperative pain control and need reduction to additive analgesia compared to Meperidine. | en |
| DOI | https://doi.org/10.5812/aapm.9997 | en |
| Keyword | Diclofenac | en |
| Keyword | Acetaminophen | en |
| Keyword | Meperidine | en |
| Keyword | Cesarean Section | en |
| Keyword | Pain | en |
| Keyword | Postoperative | en |
| Publisher | Brieflands | en |
| Title | Analgesic Efficacy of Diclofenac and Paracetamol vs. Meperidine in Cesarean Section | en |
| Type | Research Article | en |
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