Impact of Pharmaceutical Impurities in Ecstasy Tablets: Gas Chromatography-Mass Spectrometry Study
| Author | Amir Jalali | en |
| Author | Amir Hatamie | en |
| Author | Tahere Saferpour | en |
| Author | Alireza Khajeamiri | en |
| Author | Tahere Safa | en |
| Author | Foad Buazar | en |
| Issued Date | 2016-01-31 | en |
| Abstract | In this study, a simple and reliable method by gas chromatograph–mass spectrometry (GC–MS) was developed for the fast and regular identification of 3, 4-MDMA impurities in ecstasy tablets. In so doing, 8 samples of impurities were extracted by diethyl ether under alkaline condition and then analyzed by GC–MS. The results revealed high MDMA levels ranging from 37.6% to 57.7%. The GC-MS method showed that unambiguous identification can be achieved for MDMA from 3, 4-methylenedioxyamphetamine (MDA), Amphetamine (AM), methamphetamine (MA) and ketamine (Keta) compounds, respectively. The experimental results indicated the acceptable time window without interfering peaks. It is found that GC-MS was provided a suitable and rapid identification approach for MDMA (Ecstacy) tablets, particularly in the Forensic labs. Consequently, the intense MDMA levels would support the police to develop a simple quantification of impurity in Ecstasy tablets. | en |
| DOI | https://doi.org/10.22037/ijpr.2016.1824 | en |
| Keyword | Gas chromatography–Mass Spectrometry (GC–MS) | en |
| Keyword | Identification | en |
| Keyword | Determination | en |
| Keyword | MDMA | en |
| Keyword | Iran | en |
| Publisher | Brieflands | en |
| Title | Impact of Pharmaceutical Impurities in Ecstasy Tablets: Gas Chromatography-Mass Spectrometry Study | en |
| Type | Original Article | en |