The Effect of Eight Weeks High-Intensity Interval Training (HIT) on of Irisin Levels in Obese Young Men

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Background: Irisin is a myosin that increases the secretion during exercise and stimulates the white to brown adipose tissue transformation. Objectives: The current study aimed to investigate the effects of eight weeks of high-intensity interval training (HIT) on irisin levels of young obese men. Methods: The subjects of the study were divided into control and experimental groups. The experimental group performed HIT training for eight weeks (three sessions per week, each session 45 to 60 minutes with an intensity of 90% of heart rate reserve). Fasting blood sampling was done 24h before and 48h after trainings. Data were analyzed using Wilcoxon and U-Mann-Whitney tests. Results: In the experimental group, BMI was decreased (P = 0.023), and irisin was increased significantly (P = 0.005). Also, the mean differences of BMI (P = 0.049) and irisin (P = 0.031) were significant between control and experimental groups (P ≤ 0.05). Conclusions: The findings showed that eight-week of HIT could increase irisin and reduce BMI in obese young males.