Role of hypoxia and hypoxia inducible factor in physiological and pathological conditions
| Author | Mozhgan Jahani | en |
| Author | Kamran Mansouri | en |
| Issued Date | 2017-12-31 | en |
| Abstract | Introduction: Organisms are exposed to oxygen deprivation (Hypoxia) in various physiological and pathological conditions. There are different conserve evolutionary responses to counterview with this stress that primary transcriptional response to stress related to hypoxia is interceded by hypoxia-inducible factor (HIF-1) in mammals. This factor can regulate different genes that have essential roles in adaptation to this condition. In this review, the role of this factor in physiological and pathological conditions under hypoxic condition has been evaluated after examining structural features and regulation characteristics of HIF-1. | en |
| DOI | https://doi.org/ | en |
| Keyword | Hypoxia | en |
| Keyword | HIF-1 | en |
| Keyword | cancer | en |
| Publisher | Brieflands | en |
| Title | Role of hypoxia and hypoxia inducible factor in physiological and pathological conditions | en |
| Type | Review Article | en |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- 69281.pdf
- Size:
- 622.56 KB
- Format:
- Adobe Portable Document Format
- Description:
- Article/s PDF