Effect of Intraarticular injection of ozone on inflammatory cytokines in knee osteoarthritis
| Author | Masoud Hashemi | en |
| Author | Seyed Amir Mohajerani | en |
| Author | Payman Dadkhah | en |
| Orcid | Masoud Hashemi [0000-0002-8526-3074] | en |
| Orcid | Payman Dadkhah [0000-0003-4183-4581] | en |
| Issued Date | 2017-06-30 | en |
| Abstract | Introduction: Knee Osteoarthrosis is one of the most debilitating diseases. Prolotherapy includes intraarticular injection of various drugs to decrease inflammation. Injection of Intradiscal O2-O3 has reduced pain and disability of patients with low back pain due to prolapsed lumbar disk. Objective: To compare the effect of intraarticular injection of Ozone and steroids in improvement of clinical and cellular healing of knee osteoarthritis. Methods: in a randomized clinical trial, 70 patients with knee osteoarthrosis were included in the study. In Ozone group, 5 ml (35 ?g/ml) of Ozone and in steroid group 5ml (50 mg) Triamcinolone were injected intraarticular. At 1,2,and 6 month patients were followed for pain scale, disability index and IL-1? and TNF-? serum levels were measured. Results: At 1 month after injection pain scale and disability index and IL-1? and TNF-? were decreased in both groups. However, at 2 and 6 month pain scale and disability index were significantly lower in Ozone group compare to steroid group (p | en |
| DOI | https://doi.org/10.22037/jcma.v2i2.16016 | en |
| Keyword | Ozone | en |
| Keyword | inflammatory | en |
| Keyword | cytokines | en |
| Keyword | knee osteoarthritis | en |
| Publisher | Brieflands | en |
| Title | Effect of Intraarticular injection of ozone on inflammatory cytokines in knee osteoarthritis | en |
| Type | Original Articles | en |
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