How Nitric Oxide Increases in Diabetic Morphine Tolerated Male Rats
| Author | Yassar Mortada | en |
| Author | Khojasteh Khojasteh | en |
| Author | Malek Zarei | en |
| Author | Ardalan Mansouri | en |
| Author | Masoumeh Jorjani | en |
| Issued Date | 2017-04-30 | en |
| Abstract | Neuropathic pain is a complication of inflammation, infection or some diseases such as diabetes. Opioids are used as a salvage therapy for neuropathic pain but tolerance restricts their use. In our previous study, we have observed an increase of Nitric Oxide in diabetes and in morphine tolerance. This study was performed to clarify the role of inducible nitric oxide synthase, iNOS, and cationic amino acid transporter-2, CAT-2, in these conditions. | en |
| DOI | https://doi.org/10.22037/ijpr.2017.2056 | en |
| Keyword | Diabetes | en |
| Keyword | Morphine tolerance | en |
| Keyword | Nitric Oxide Synthase | en |
| Keyword | Cationic Amino Acid Transporter-2 | en |
| Keyword | Male Rat | en |
| Publisher | Brieflands | en |
| Title | How Nitric Oxide Increases in Diabetic Morphine Tolerated Male Rats | en |
| Type | Original Article | en |
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