Plasmapheresis with Convalescent Plasma as a Rescue Therapy for COVID-19 Patients: A Case Series

AuthorJamshid Vafaeemaneshen
AuthorSeyed Hassan Adelien
AuthorAkram Asgharien
AuthorFateme Sadat Razaviniaen
OrcidJamshid Vafaeemanesh [0000-0002-9063-2639]en
OrcidSeyed Hassan Adeli [0000-0001-5970-7551]en
OrcidAkram Asghari [0000-0001-6948-2675]en
Issued Date2021-10-31en
AbstractOn December 29, 2019, an epidemic of an infectious disease caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) was declared in Wuhan, China. The first case of COVID-19 in Iran (Qom Province) was reported in February 2020, and within a short period, the number of infected cases increased rapidly around the country. Evidence suggests that the levels of pro-inflammatory cytokines are high in critically ill patients, and there is a correlation between the high level of cytokines and the pathogenesis of COVID-19; consequently, COVID-19 may have complications, such as acute respiratory distress syndrome (ARDS) and even death. These inflammatory factors can lead to a cytokine storm, while counteracting this storm seems to be an effective therapeutic approach. In this case series, we reported two critically ill patients with COVID-19, undergoing plasmapheresis with convalescent plasma, corticosteroid therapy, and interferon administration.en
DOIhttps://doi.org/10.5812/archcid.111405en
KeywordPlasmapheresis with Convalescent Plasmaen
KeywordRescue Therapyen
KeywordCOVID-19 Patientsen
PublisherBrieflandsen
TitlePlasmapheresis with Convalescent Plasma as a Rescue Therapy for COVID-19 Patients: A Case Seriesen
TypeCase Reporten

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