Effects of Tarragon Powder on Glucose Metabolic Changes, Lipid Profile and Antioxidant Enzyme Levels in Type 2 Patients with Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Clinical Trial
| Author | Hossein Khadem Haghighian | en |
| Author | Mohammadreza Shiran | en |
| Author | Ozra Akha | en |
| Author | Zahra Ghafouri | en |
| Author | Ehsan Ghaedi | en |
| Author | Sara Bayat | en |
| Author | Mohammad Ali Mazloomi | en |
| Author | Gholamreza Houshmand | en |
| Orcid | Zahra Ghafouri [0000-0002-5524-6521] | en |
| Orcid | Gholamreza Houshmand [0000-0002-0790-098X] | en |
| Issued Date | 2021-02-28 | en |
| Abstract | Background: The antioxidant and anti-inflammatory properties of tarragon make it known as an antidiabetic plant. Diabetes mellitus, an endocrine, metabolic disease, is a leading global health emergency and associated with serious complications. Objectives: This study aimed to assess the effects of tarragon powder supplementation on glucose metabolism, lipid profile, and antioxidant status in the diabetic population. Methods: Patient screening and selection for this clinical trial lasted one month. Tarragon supplement consumption by patients lasted 2 months (8 weeks); meanwhile, they were followed up. Sixty male and female patients with type 2 diabetes were randomly assigned to the tarragon receiver group (n = 30) and placebo receiver group (n = 30). The intervention group received a tarragon capsule (500 mg) 3 times a day, and the control group received placebo capsules. Fasting blood glucose (FBG), two-hour postprandial glucose (2-hpp), glycated hemoglobin (HbA1c), insulin, lipid, and antioxidant profile were evaluated at the start and the end of the research. Results: In the tarragon receiver group, FBG, 2-hpp, HbA1c%, insulin resistance, lipid, and antioxidant profile significantly improved, compared to the placebo group, after adjuvant therapy with tarragon (P < 0.05). Conclusions: Supplementation with tarragon powder in type II patients with diabetes for 2 months exerts a beneficial effect on improving the glycemic profile, lipid profile, and antioxidant status. | en |
| DOI | https://doi.org/10.5812/jjnpp.102469 | en |
| Keyword | Tarragon | en |
| Keyword | Type 2 Diabetes | en |
| Keyword | Glycemic Status | en |
| Keyword | Lipid Profile | en |
| Keyword | Clinical Trial | en |
| Publisher | Brieflands | en |
| Title | Effects of Tarragon Powder on Glucose Metabolic Changes, Lipid Profile and Antioxidant Enzyme Levels in Type 2 Patients with Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Clinical Trial | en |
| Type | Research Article | en |
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