The Role of Signaling Pathway on Osteoprogenitor Cell Behavior and Bone Formation

AuthorMaedeh Hashemien
AuthorVahid Shakerien
AuthorHaleh Mosallaeien
AuthorMona Kholdebarinen
AuthorMohamad Bakhtiarien
AuthorMasoomeh Mohamadpouren
AuthorSaeed Gholamien
AuthorSeyed Amir Yazdanparasten
Issued Date2018-06-30en
AbstractDifferent biomarkers and signaling pathways are involved in bone development. These factors lead to different osteoprogenitor cell reactions. Proliferation, migration, and differentiation of osteoprogenitor cells is induced by different intracellular and extracellular molecular signaling pathways. As mesenchymal stem cells (MSCs) and their differentiation during repair and development of bone processes have significant roles, it is believed that sensible molecular signaling pathways involvement is vital to the development of bone formation, bone substitute materials, and bone repair. This study reviews various keys of signaling pathway that terminate proliferation, migration, and differentiation of osteoprogenitor cells.en
DOIhttps://doi.org/10.5812/thrita.81485en
KeywordBoneen
KeywordSignaling Pathwaysen
KeywordOsteoprogenitoren
KeywordProliferationen
KeywordDifferentiationen
PublisherBrieflandsen
TitleThe Role of Signaling Pathway on Osteoprogenitor Cell Behavior and Bone Formationen
TypeReview Articleen

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