Strategies for Preventing of <i>Fusarium</i> Species Infections in Burn Patients: A Systematic Review

Abstract

Context: Burn infections are a major public health problem for individuals suffering from burn wounds. Objectives: The present study was conducted with the aim of analyzing the literature on Fusarium infection in burn patients to determine the mortality rate, types of fungal infections, cultures, and prevention strategies. Methods: This systematic review analyzes scientific literature related to Fusarium species (spp.) infections in burn patients. A search was performed to identify relevant studies in PubMed, Web of Science, Scopus databases, and Google Scholar search engine from 2000 to August 2025 using specific keywords and their equivalents. The inclusion criteria comprised English-language articles pertinent to the research objectives and the subject area of Fusarium infections. Non-English-language articles or studies lacking full-text availability were excluded. Content analysis was employed to examine the data. Results: The first section of the findings shows that 34 related articles were identified concerning Fusarium spp. infections. The highest mortality rate was 45% in burn patients with Fusarium fungus. The detected spp. was Fusarium solani based on diagnostic samples taken from biopsy and histopathological examinations. The type of treatment was amphotericin B and voriconazole, and 83% of burns occurred among men. Conclusions: Fusarium infections among burn patients were among the factors affecting mortality. Strategies to prevent and reduce mortality in burn patients with Fusarium spp. infections include early diagnosis, appropriate antifungal treatment, air ventilation, patient isolation, elimination of flowers, and use of chemoprophylaxis. Additionally, healthcare workers are required to distinguish predisposing factors for visceral fungal disease.