Low Grade Extrauterine Endometrial Stromal Sarcoma Arising from Peritoneum Endometriosis: A Case Report and Literature Review
| Author | Hamidreza Haghighatkhah | en |
| Author | Seyedeh Mahdieh Ghasimi | en |
| Author | Afshin Moradi | en |
| Author | Seyed Soran Ghafouri | en |
| Author | Tayeb Hosseini | en |
| Orcid | Hamidreza Haghighatkhah [0000-0001-5411-0609] | en |
| Orcid | Afshin Moradi [0000-0003-1544-0992] | en |
| Issued Date | 2024-12-31 | en |
| Abstract | Introduction: Endometrial stromal sarcoma (ESS) is an uncommon condition that accounts for approximately 0.2% of all reproductive tract malignancies. Among the various subtypes of ESS, low-grade extrauterine endometrial stromal sarcoma (LG-EESS) is even rarer and has only been reported in a limited number of case studies. Case Presentation: We reported a case of LG-EESS in a 35-year-old woman with a five-year history of stage IV endometriosis. The patient presented with chronic abdominopelvic pain and dysmenorrhea. Transvaginal ultrasound showed bilateral tubo-ovarian complexes with multicystic structures, while MRI revealed solid lesions with T1 iso signal, T2 hypersignal, and diffusion restriction, indicating metastatic implantation extending to the peritoneum and subhepatic region. A core needle biopsy confirmed LG-EESS, and immunohistochemistry showed CD10 positivity, aiding in the diagnosis and distinguishing it from other tumors. Conclusions: Our case highlights the potential utility of preoperative diagnostic imaging, particularly MRI, in the evaluation of LG-EESS. Additionally, it emphasizes the importance of considering the possibility of extrauterine ESS, as this tumor exhibits histopathological features and clinical behavior similar to its uterine counterpart. | en |
| DOI | https://doi.org/10.5812/ijcm-148144 | en |
| Keyword | Endometriosis | en |
| Keyword | Low Grade Extrauterine Endometrial Stromal Sarcoma | en |
| Keyword | Peritoneum | en |
| Keyword | Magnetic Resonance Imaging | en |
| Publisher | Brieflands | en |
| Title | Low Grade Extrauterine Endometrial Stromal Sarcoma Arising from Peritoneum Endometriosis: A Case Report and Literature Review | en |
| Type | Case Report | en |