SARS-CoV-2 Infection in Iranian People Living with Human Immunodeficiency Virus-1 Infection

AuthorSaba Garshasbien
AuthorFarah Bokharaei-Salimen
AuthorKhadijeh Khanalihaen
AuthorSeyed Jalal Kianien
AuthorSaeed Kalantarien
AuthorMahin Jamshidi Makianien
AuthorArezoo Marjanien
AuthorFarzaneh Dehghani-Dehejen
AuthorRoghayeh Babaeien
AuthorMohsen Sadeghien
AuthorMohammad Abbasi-Kollien
OrcidSaba Garshasbi [0000-0001-7564-7309]en
OrcidFarah Bokharaei-Salim [0000-0002-5367-0847]en
OrcidKhadijeh Khanaliha [0000-0003-3264-8496]en
OrcidSeyed Jalal Kiani [0000-0002-5499-8924]en
OrcidSaeed Kalantari [0000-0001-9896-4139]en
OrcidMahin Jamshidi Makiani [0000-0001-7052-5599]en
OrcidFarzaneh Dehghani-Dehej [0000-0002-8440-7996]en
OrcidRoghayeh Babaei [0000-0002-6203-8640]en
OrcidMohsen Sadeghi [0000-0002-9180-333X]en
OrcidMohammad Abbasi-Kolli [0000-0003-2661-9613]en
Issued Date2022-01-31en
AbstractBackground: A novel Coronavirus first emerging in Wuhan, China, was named severe acute respiratory syndrome Coronavirus 2 (SARS‐CoV‐2). The disease caused by SARS‐CoV‐2 is known as Coronavirus disease 2019 (COVID‐19). HIV-1 infected individuals may be at risk of COVID-19. Objectives: This cross-sectional study evaluated the SARS-CoV-2 infection rate and COVID-19 prevalence among Iranian HIV-1-infected people. Methods: The study was conducted on 155 HIV-1-infected patients from June 2020 to October 2020. COVID-19 Ab (IgG) was detected using an enzyme immunoassay in serum specimens. Furthermore, nasopharyngeal and oropharyngeal specimens were collected. Then, the genomic RNA of SARS‐CoV‐2 was detected using a real-time polymerase chain reaction (RT-PCR). Clinical symptoms of the studied participants with and without COVID-19 were examined. Results: Of 155 HIV-1-infected individuals, 12 (7.7%) had positive real-time PCR results for SARS-CoV-2. Out of 12 (7.7%) patients with COVID‐19, four (33.3%) were males. Anti-COVID Ab (IgG) was detected in 10 (6.5%) participants, of whom eight (80.0%) were males. The most common COVID-19 clinical symptoms, including dry cough, fever, runny nose, anosmia, and hypogeusia, were observed in seven (58.3%), five (41.7%), five (41.7%), five (41.7%), and five (41.7%) patients with COVID-19, respectively. Conclusions: A recent study has shown that the risk of SARS‐CoV‐2 infection in HIV-infected individuals is similar to that in the general population.en
DOIhttps://doi.org/10.5812/jjm.121929en
KeywordHIV-1 Infectionen
KeywordSARS-CoV-2en
KeywordCOVID-19en
KeywordClinical Symptomsen
PublisherBrieflandsen
TitleSARS-CoV-2 Infection in Iranian People Living with Human Immunodeficiency Virus-1 Infectionen
TypeResearch Articleen

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