Adiponectin is a Good Marker for Metabolic State among Type 1 Diabetes Mellitus Patients
| Author | Hamdollah Karamifar | en |
| Author | Narges Habibian | en |
| Author | Gholamhosein Amirhakimi | en |
| Author | Zohre Karamizadeh | en |
| Author | Abbas Alipour | en |
| Accessioned Date | 2023-12-24T16:00:48Z | |
| Available Date | 2023-12-24T16:00:48Z | |
| Issued Date | 2013-06-30 | en |
| Abstract | Objective: Adiponectin is secreted from adipose tissue. This hormone has a fundamental role in pathogenesis of insulin resistance, and has anti-inflammatory and anti-atherogenic effects. The objectives of this study were to compare serum adiponectin level between type 1 diabetics and healthy people and to assess its related factors, and also to determine the relationship between adiponectin and metabolic state. Methods: This was a case control study involving 60 diabetics (25 good and 35 poor metabolic controlled) and 28 healthy persons (younger than 18 years old). The data about demographic (age and sex), clinical and paraclinical characteristics [body mass index (BMI), duration of disease, puberty state, and glycosylated hemoglobin (HbA1c) and adiponectin level in serum] were collected. Determinants of adiponectin were assessed using univariate and multiple linear regression analyses. Findings: Mean (±SD) serum adiponectin level in healthy persons, good-controlled and poor-controlled type 1 diabetes mellitus patients were 9.16 (±4.2) μg/cc, 10.89 (±4.48)μg/cc, and 15.92 (±8.26)μg/cc, respectively. Post hoc analysis revealed that differences of adiponectin between poor- and good-controlled type 1 diabetes mellitus patients (P=0.01) and between healthy persons and poor controlled type 1 diabetes mellitus (P | en |
| DOI | https://doi.org/ | en |
| URI | https://repository.brieflands.com/handle/123456789/35073 | |
| Keyword | Cytokines | en |
| Keyword | Adiponectin | en |
| Keyword | Type 1 Diabetes Mellitus | en |
| Keyword | Glycosylated Hemoglobin | en |
| Keyword | Puberty | en |
| Publisher | Brieflands | en |
| Title | Adiponectin is a Good Marker for Metabolic State among Type 1 Diabetes Mellitus Patients | en |
| Type | Research Article | en |