High Serum Levels of TGF-? in Iranians With Chronic HBV Infection
| Author | Hossein Khorramdelazad | en |
| Author | Gholamhossein Hassanshahi | en |
| Author | Behzad Nasiri Ahmadabadi | en |
| Author | Mohammad Kazemi Arababadi | en |
| Issued Date | 2012-10-31 | en |
| Abstract | Background: The transforming growth factor-? (TGF-?) is an important cytokine with anti-inflammatory properties. Objectives: The main purpose of this study was to compare the serum levels of TGF-? in a group of chronic HBV infected (CHB) patients as well as healthy individuals from South-East of Iran. Patients and Methods: Sixty patients with CHB as well as sixty healthy individuals were enrolled in the study. ELISA technique was applied to measure the serum levels of TGF-? in both groups. Results: Our results revealed that the serum levels of TGF-? were significantly increased in CHB patients in compare to healthy controls. Conclusions: According to this result, it may be concluded that high serum levels of TGF-? may be a mechanism by which immune response against HBV is suppressed. | en |
| DOI | https://doi.org/10.5812/hepatmon.7581 | en |
| Keyword | Hepatitis B | en |
| Keyword | Chronic | en |
| Keyword | Transforming Growth Factor Beta | en |
| Publisher | Brieflands | en |
| Title | High Serum Levels of TGF-? in Iranians With Chronic HBV Infection | en |
| Type | Brief Report | en |
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