Leptospirosis and COVID-19 Co-Infection Manifesting as an Enhanced Thrombotic Phenomenon

Abstract

Clinical manifestations of COVID-19 range from mild self-limiting illness to multi-organ dysfunction and acute respiratory distress syndrome (ARDS). Leptospirosis too manifests as mild or asymptomatic infection and only small number of patients progress to ARDS and develop systemic manifestation. COVID-19 and leptospira co infection can have fatal outcome because of augmented pathophysiological manifestations of both the disease. We here describe a case of leptospira and COVID-19 coinfection in a patient who had poor outcomes due to multi-organ involvement.