Phytochemical Investigation on <i>Euphorbia macrostegia </i>(Persian wood spurge)

AuthorSomayeh Zareen
AuthorMehrorang Ghaedien
AuthorRamin mirien
AuthorSven Heilingen
AuthorMojtaba Asadollahien
AuthorIan T. Baldwinen
AuthorAmir Reza Jassbien
Issued Date2015-01-31en
AbstractEuphorbia macrostegia or Persian wood spurge is one of the seventeen endemic plants of this genus in Iran. Three triterpenoids, 24-methylenecycloartan-3β-ol (1), butyrospermol (2) and cycloartenol (3) and three diglycerides, 1,2-di-O-α-linolenoyl-sn-glycerol (4), 1-O-linoleoyl-3-O-palmitoyl-sn-glycerol (5) and 1-O-α-linolenoyl-2-O-palmitoyl-sn-glycerol (6) were isolated from the hexane soluble part of methanol-dichloromethane extracts of the aerial parts of Euphorbia macrostegia Boiss. The structures of all compounds were elucidated using different spectroscopy methods including, 1H NMR, 13C NMR, HSQC, HMBC, EI-MS and IR. The triterpenes and the unsaturated fatty acids moieties of the diglycerides isolated from the plant were reported previously to have analgesic, anticancer, bactericidal and antifungal activity. Here, we show that E. macrostegia is a new source for the above mentioned biologically active compounds.en
DOIhttps://doi.org/10.22037/ijpr.2015.1606en
KeywordEuphorbiaceaeen
Keyword<i>Euphorbia macrostegia</i>en
KeywordCycloartane triterpenoidsen
KeywordDiglycerides of fatty acidsen
PublisherBrieflandsen
TitlePhytochemical Investigation on <i>Euphorbia macrostegia </i>(Persian wood spurge)en
TypeOriginal Articleen

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