Effectiveness of Vitamin D Supplement Therapy in Chronic Stable Schizophrenic Male Patients: A Randomized Controlled Trial
| Author | Fatemeh Sheikhmoonesi | en |
| Author | Mehran Zarghami | en |
| Author | Shima Mamashli | en |
| Author | Jamshid Yazdani Charati | en |
| Author | Romina Hamzehpour | en |
| Author | Samineh Fattahi | en |
| Author | Rahil Azadbakht | en |
| Author | Zahra Kashi | en |
| Author | Shahram Ala | en |
| Author | Mona Moshayedi | en |
| Author | Habibollah Alinia | en |
| Author | Narjes Hendouei | en |
| Issued Date | 2016-10-31 | en |
| Abstract | In this study, the aim was to determine whether adding vitamin D to the standard therapeutic regimen of schizophrenic male patients with inadequate vitamin D status could improve some aspects of the symptom burden or not. This study was an open parallel label randomized clinical trial. Eighty patients with chronic stable schizophrenia with residual symptoms and Vitamin D deficiency were recruited randomly and then received either 600000 IU Vitamin D injection once along with their antipsychotic regimen or with their antipsychotic regimen only. Serum vitamin D was measured twice: first at the baseline and again on the fourth month. Positive and Negative Syndrome Scale (PANSS) was assessed at the baseline and on the fourth month. During the study, the vitamin D serum changes in vitamin group and control group were 22.1 ± 19.9(95%CI = 15.9-28.8) and 0.2 ± 1.7(95%CI = 0.2-0.8) (ng/mL) (p | en |
| DOI | https://doi.org/10.22037/ijpr.2016.1942 | en |
| Keyword | Vitamin D deficiency | en |
| Keyword | PANSS negative subscale score | en |
| Keyword | PANSS positive subscale score Positive | en |
| Keyword | Schizophrenic patients | en |
| Keyword | Antipsychotic drugs | en |
| Publisher | Brieflands | en |
| Title | Effectiveness of Vitamin D Supplement Therapy in Chronic Stable Schizophrenic Male Patients: A Randomized Controlled Trial | en |
| Type | Original Article | en |
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