Investigation of the Possible Risk Factors Associated with Subclinical Left Ventricular Dysfunction Assessed by 2D Speckle Tracking Echocardiography in Patients with Type 2 Diabetes Mellitus and Normal Ejection Fraction

Abstract

Background: Subclinical left ventricular dysfunction is an important predictor of cardiovascular death, detected via the global longitudinal strain (GLS) echocardiographic parameter. While T2DM is associated with a worse GLS, it is not cost-effective to perform 2D speckle tracking echocardiography for all asymptomatic T2DM patients to screen for early signs of subclinical left ventricular dysfunction.