Epidemiology and Molecular Detection of HAV, HBV, and HCV in Patients with Acute Hepatitis Symptoms in Ahvaz
| Author | Maryam Tabasi | en |
| Author | Manoochehr Makvandi | en |
| Author | Ali Teimoori | en |
| Author | Maryam Dastoorpoor | en |
| Author | Hamid Moradzadegan | en |
| Author | Mahdi Parsanahad | en |
| Author | Roya Pirmoradi | en |
| Author | Chiman Karami | en |
| Orcid | Manoochehr Makvandi [0000-0003-2510-3033] | en |
| Orcid | Maryam Dastoorpoor [0000-0001-5268-334X] | en |
| Issued Date | 2018-05-31 | en |
| Abstract | Background: Viral hepatitis has emerged as a major public health problem leading to disproportionate degrees of morbidity and mortality worldwide. Objectives: This study describes epidemiology of hepatitis A virus (HAV), hepatitis B virus (HBV), and hepatitis C virus (HCV), and associated risk factors in patients with acute hepatitis symptoms in southwest of Iran (Ahvaz). Methods: A total of 150 serum samples from patients with elevated serum aminotransferase levels were subjected to serological and molecular assays. Results: The sero-prevalence of HAV, HBV, and HCV was 79.3%. Furthermore, HAV, HBV, and HCV nucleic acids were detected in 28%, 18.7%, and 22.7% of samples, respectively. All HAV cases were categorized in the IB genotype and HBV isolates belonged to genotype D. Hepatitis C virus RNA-positive samples were clustered in genotypes 1a (38.3%) and 3a (61.7%). The authors found that some risk factors, such tattooing and traveling to endemic areas, had a crucial role in rising of viral hepatitis frequency in Ahvaz city. Conclusions: These results document the prevalence of circulating viral hepatitis in Ahvaz city and may draw attention to the necessity for a comprehensive program to control viral hepatitis in this region. | en |
| DOI | https://doi.org/10.5812/jjm.63317 | en |
| Keyword | Hepatitis A Virus (HAV) | en |
| Keyword | Hepatitis B Virus (HBV) | en |
| Keyword | Hepatitis C Virus (HCV) | en |
| Keyword | Molecular Epidemiology | en |
| Keyword | Risk Factor | en |
| Keyword | Polymerase Chain Reaction | en |
| Keyword | Tattooing | en |
| Publisher | Brieflands | en |
| Title | Epidemiology and Molecular Detection of HAV, HBV, and HCV in Patients with Acute Hepatitis Symptoms in Ahvaz | en |
| Type | Research Article | en |