Development of a Sensitive and Rapid Method for Determination of Acrylamide in Bread by LC-MS/MS and Analysis of Real Samples in Iran IR
| Author | Samira Eslamizad | en |
| Author | Farzad Kobarfard | en |
| Author | Kimia Tabib | en |
| Author | Hassan Yazdanpanah | en |
| Author | Jamshid Salamzadeh | en |
| Issued Date | 2020-01-31 | en |
| Abstract | A new sample preparation procedure and a liquid chromatography–tandem mass spectrometry (LC–MS/MS) method were developed for the quantitative analysis of acrylamide in bread. The method is based on sample extraction in methanol, purification with Carrez solutions and clean- up with Primary Secondary Amine (PSA).The developed method offers an efficient, inexpensive, easy sample preparation and very sensitive procedure for determination of acrylamide in bread. The use of spiked calibration curves for constructing the calibration curve substantially reduced adverse matrix-related effects. Recoveries were between 96 and 105.3%. Good results were obtained with respect to repeatability (RSDs | en |
| DOI | https://doi.org/10.22037/ijpr.2019.111994.13474 | en |
| Keyword | Food safety | en |
| Keyword | Acrylamide | en |
| Keyword | Method validation | en |
| Keyword | Sangak bread | en |
| Keyword | LC-MS/MS | en |
| Keyword | Iran IR | en |
| Publisher | Brieflands | en |
| Title | Development of a Sensitive and Rapid Method for Determination of Acrylamide in Bread by LC-MS/MS and Analysis of Real Samples in Iran IR | en |
| Type | Original Article | en |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- ijpr-19-413.pdf
- Size:
- 598.79 KB
- Format:
- Adobe Portable Document Format
- Description:
- Article/s PDF