Measurement of the Corpus Callosum Using Magnetic Resonance Imaging in the North of Iran
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Date
2011-12-31
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Abstract
Background: Morphometric measurements of the corpus callosum (CC) are important to have normative values according to sex, age and race/ethnicity.Objectives: This study was done to measure the size of CC and to identify its gender- and age-related differences in the North of Iran.Patients and Methods: The size of CC on midsagittal section was measured in 100 (45 males, 55 females) normal subjects using magnetic resonance imaging (MRI) admitted to the Kowsar MRI center in Gorgan–Northern Iran.Longitudinal and vertical dimensions of the CC, longitudinal and vertical lengths of the brain and the length of genu and splenium were measured. Data were analyzed by student’s unpaired t test, ANOVA and regression analysis.Results: The anteroposterior length and vertical dimension of the CC, the length of genu and splenium were larger in males than in females, but these differences were not significant. The anteroposterior and vertical lengths of the brain were significantly larger in males than in females (P < 0.05). The length of CC increased with age and regression equations for predicting age were derived from the length of the CC. There was also a positive significant correlation between the anteroposterior length of the CC and the length of the brain and vertical dimension of the CC.Conclusions: This study showed that various CC parameters vary with the values documented in the Caucasian, Indian and Japanese population.
Implication for health policy/practice/research/medical education:This study indicates that the size of corpus callosum is related to gender and age which may help in finding possible changes in degenerative diseases and correcting the target zones in brain stereotactic surgery.
Please cite this paper as:Mohammadi MR, Zhand P, Mortazavi Moghadam B, Golalipour MJ. Measurement of the Corpus Callosum Using Magnetic Resonance Imaging in the North of Iran. Iran J Radiol. 2011;8(4):218-23. DOI: 10.5812/iranjradiol.4495
Copyright © 2011, Tehran University of Medical Sciences and IranianSociety of Radiology. Published by Kowsar Corp. All rights reserved.