Diagnostic Value of Fasting Plasma Glucose in Screening of Gestational Diabetes Mellitus
| Author | Z Kashi | en |
| Author | SH Borzouei | en |
| Author | O Akha | en |
| Author | N Moslemizadeh | en |
| Author | HR Zakeri | en |
| Author | A Mohammad Poor | en |
| Author | R Banafti | en |
| Author | L Shahbaznezhad | en |
| Orcid | Z Kashi [0000-0002-4683-1323] | en |
| Issued Date | 2007-01-31 | en |
| Abstract | Today, although screening tests for Gestational Diabetes Mellitus (GDM) are available, they are time-consuming and expensive; hence perform-ing tests that are cheaper but have higher sensi-tivity and specificity seems necessary. The aim of this study was to determine a cut off point of fasting plasma glucose (FPG) for screening GDM. Materials and Methods: In this clinical trial, 200 pregnant women aged ≥25 years referring to a perinatal clinic were selected. Inclusion criteria re-quired having one of the following risk factors: His-tory of recurrent abortion, GDM, pre-eclampsia, macrosomia, still birth, or diabetes mellitus(DM) in first degree family or pre gestational body mass index ≥25kg/m2. All participants underwent a 50 g glucose challenge test (GCT) between the 24th and 28th gestational week. If 1-hour plasma glu-cose was over 130 mg/dL, a 3-hour 100g oral glu-cose tolerance test (OGTT) was recommended. The diagnosis of GDM was made based on ADA recommendations. Results: Of 200 participants, 65 women had posi-tive GCT, of which 58 (response rate 89%) were referred for 100g OGTT and 20 (10%) were di-agnosed with GDM. The under curve area for FPG of 0.85 and the FPG level of 91.5 mg/dL, showed highest sensitivity -80%, and specificity -92%, respectively in the diagnosis of GDM. Significant difference was observed between the GDM and normal groups for mean age, gravid-ity, parity and BMI (P | en |
| DOI | https://doi.org/ | en |
| Keyword | Fasting plasma glucose | en |
| Keyword | Gestational diabetes mellitus | en |
| Keyword | 50 gr glucose challenge test. | en |
| Publisher | Brieflands | en |
| Title | Diagnostic Value of Fasting Plasma Glucose in Screening of Gestational Diabetes Mellitus | en |
| Type | Research Article | en |
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