Effect of Fumaria Parviflora hydro alcoholic extract on induced carageenan inflammation in male rat paw

Issued Date	2013-06-30	en
Abstract	Background: This study investigated the anti-inflammatory effect of Fumaria Parviflora due to its Fumaric acid, flavonoid and phenolic compounds for skin diseases, relieves itching and eczema. Material and methods: Male wistar rats (ranging 150-180g in weight) were used. For preparation of the hydro alcoholic extract, Plant powdered were macerated in ethanol 70%, then extract were concentrated for further use. Five treatment Animal groups received dose of 200, 400, 600, 800 or 1000 mg/kg of Fumaria Parviflora extract, Positive control group received a dose of 300 mg/kg aspirin and negative control group received serum physiology solution with dose of 5 ml/kg via intra-peritoneal injection of traits. After half an hour, 100 micro liters of carageenan 1%was subcutaneously injected into the rats paw and then the volume of the rats paws were evaluated using PLethysmometer apparatus.once every hours between the first and fifth hours Results: 200 and 400 mg/kg doses of extract had less effect on decreasing the paws edema in comparison with animal group received aspirin (p0.05).	en
DOI	https://doi.org/	en
Publisher	Brieflands	en
Title	Effect of Fumaria Parviflora hydro alcoholic extract on induced carageenan inflammation in male rat paw	en
Type	Research Article	en

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